INTRODUCTION A reduction in homocysteine concentration due to the use of supplemental folic acid is well recognized, although evidence of the same effect for natural folate sources, such as fruits and vegetables (FV), is lacking. The traditional statistical analysis approaches do not provide further information. As an alternative, quantile regression allows for the exploration of the effects of...

Although the heavy and light chain domains of some antibody variable region fragments (Fvs) readily dissociate under physiological conditions, the Fvs are stable in the presence of antigen. This 'antigen-driven Fv stabilization mechanism' was applied to the selection of clones with specificity toward target antigens. The results can be summarized as follows. (i) Some of the residues in the heav...

Two murine monoclonal antibodies, N901 (anti-CD56) and anti-B4 (anti-CD19), were humanized by a process we call "resurfacing." A systematic analysis of known antibody structures has been used to determine the relative solvent accessibility distributions of amino acid residues in murine and human antibody variable (Fv) regions and has shown that the sequence alignment positions of surface amino ...

Correlative high speed AFM and florescence microscopy to reveal membrane reshaping by septins.

We have previously shown that the variable domains of the monoclonal antibody anti-Tac [anti-Tac(Fv)] can be fused to derivatives of Pseudomonas exotoxin (PE) or diphtheria toxin (DT) to produce recombinant immunotoxins that kill interleukin-2 (IL-2) receptor-bearing cells. We now report that two of these single-chain recombinant immunotoxins, anti-Tac(Fv)-PE40KDEL and DT388-anti-Tac(Fv), are c...

Objective: Fruit and Vegetable (FV) intake-a modifiable risk factor for chronic diseases-is lower among racial/ethnic minorities and low SocioEconomic Status (SES) groups when compared to other populations. The Theory of Planned Behavior (TPB) is one theoretical model studied to explain and influence individual health behaviors, including FV intake, in middle class populations, but not exclusiv...

It is shown in this paper that all internal nodes with the same subtree can be treated as a single state in a code tree of a fixed-to-variable length code (FV code) when we use CapocelliGrango-Vaccaro algorithm and Even algorithm to check whether the FV code has a self-synchronizing string. Based on this reduced state representation, we characterize three types of code trees with no self-synchr...

Introducción. Plantas expuestas a condiciones de estrés alteran su funcionamiento y generan respuestas fisiológicas que afectan desempeño agronómico. En el cultivo Cannabis medicinal, son escasos los trabajos investigación sobre la fisiología planta interacción con factores bióticos. Objetivo. Determinar variables indicadoras en diferentes etapas fenológicas plantas invernadero bajo fitosanitar...