Alopecia areata is common scalp complaint, seen in any age group. It an auto immune disorder effecting the hair follicles, causing loss of patches. constitutes a life time risk approximately 2%. does not carry significant sex or ethnic predominance. Peak incidence occurs second and third decades most patients experience onset before fourth decade. Homoeopathy 2nd widely used therapy all over wo...

Some hybrids of vinca alkaloids and phomopsin A, linked by a glycine pattern, have been synthesized in one or two steps, by an insertion reaction and shown to inhibit microtubule assembly. These compounds have been elaborated in order to interact with both the "vinca site" and the "peptide site" of the vinca domain in tubulin. Two out of three hybrids are potent inhibitors of microtubules assem...

Antimicrotubule Vinca alkaloids, such as vinblastine and vincristine, interfere with the dynamics of microtubules and have shown significant cell killing activity in a variety of tumor cells through induction of apoptosis. The mechanism by which Vinca alkaloids induce apoptosis is not entirely clear. In this study, we found that glucocorticoids inhibit Vinca alkaloid-induced apoptosis without a...

Abstract Important natural antimicrobial compounds derived from Vinca minor L. plant contain a wide variety of secondary metabolites which are useful for brain health (increasing blood circulation in the brain, supporting metabolism, preventing memory loss and problems with concentration premature aging cell), externally they play role tissue repair skin lesion healing. The testing activity alc...

Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects. They have been used to treat diabetes, high blood pressure and have been used as disinfectants. The vinca alkaloids are also important for being cancer fighters. There ar...

Developing new methods for chemotherapy drug delivery has become a topic of great concern. Vinca alkaloids are among the most widely used chemotherapy reagents for tumor therapy; however, their side effects are particularly problematic for many medical doctors. To reduce the toxicity and enhance the therapeutic efficiency of vinca alkaloids, many researchers have developed strategies such as us...

Cancer is deadliest disease ever known. Vinca extract has the potential and beneficial in treating various cancer conditions. However, till date no known syrup of plant or its been formulated. a debilitated condition formulation evaluation herbal alcoholic vinca may serve patient compliance ease administration by oral route. The was formulated using Vinca. Syrups are easy to formulate help over...

The role of oxidative stress is known among the patients diabetes as level reactive oxygen species was high diabetic patients. This generated in due to continuous glucose levels that cause decrease defence mechanism for antioxidant enzymes within body. reduction leads towards generation hydroxyl radicals consequently results lipid peroxidation. objective this study examine efficacy Vincamine ex...