Vitex agnus-castus (VAC) is a plant that has recently been used to treat the symptoms of menopause, by its actions on the central nervous system. However, little is known about its actions on disturbances in lipid metabolism and nonalcoholic fat liver disease (NAFLD), frequently associated with menopause. Ovariectomized (OVX) rats exhibit increased adiposity and NAFLD 13 weeks after ovary remov...

Conservation and preservation concerns have led to efforts to understand mechanisms of invasiveness and the effects these mechanisms have on the environment. Vitex rotundifolia L. f. [beach vitex (BV)] was introduced as a salt-tolerant woody ground cover, but it has since become invasive on primary and secondary dunes in coastal areas of the southeastern United States. Much of its invasive pote...

According to their accessibility and lower cost-effectiveness when compared synthetic chemical treatments, medicinal wild plants herbs have been used for ages as beneficial tools in the management of many diseases. The popular plant Vitex agnus-castus, which is indigenous Mediterranean region widely distributed Europe, Asia, North Africa, treat a number conditions diseases, including premenstru...

BACKGROUND Aging is associated with the loss of endocrine function. In this study, Vitex agnus-castus (Vitex), which has antioxidant effects and high levels of phytoestrogen, was investigated with regard to the hypothalamic-pituitary-gonadal axis and antioxidant indices in natural aging and in a d-galactose induced aging model in female mice. METHODS The mice were subcutaneously injected with...

objective(s) there is well documented evidence for the increase in widespread use of complementary and alternative medicine in the treatment of physical and psychiatric symptoms and disorders within the populations. in the present study, we investigated the influence of vitex agnus-castus (vitex) on anxiety-like behaviors of rats. materials and methods elevated plus maze which is one of the met...

The main goal of this study was to evaluate antioxidant activity of Vitex agnus-castus aerial parts and also to investigate the main phytoconstituents in the plant extracts. Nhexane, dichloromethane, ethyl acetate and methanol 80% extract were tested for free radical scavenging activity on model reaction with stable 2,2-diphenyl-1-picrylhydrazyl radical (DPPH). The results showed that ethyl ace...

Local medicinal plants from Madina, Saudi Arabia, are used to cure various diseases. However, some can cause adverse health effects. Five different medicinal plants were collected in the city of Madina: mahareeb (Cymbopogon), sheeh (Artemisia), harjal (Cynanchum argel delile), nabipoot (Equisetum), and kafmariam (Vitex agnus-castus). In total, four toxic elements including Al, Pb, As, and Cd we...