Background&Aims: Vancomycin Resistant Enterococci (VRE) are among the most common nosocomial pathogens worldwide. The intestinal tract provides a major source for transmission of these bacteria. Probiotics are living microorganisms that moderate use of them has inhibitory effect on intestinal colonization by enteric pathogens. We examined the effect of Lactobacillus rhamnosus GG (LGG) on inhibi...

The principal objective of this study was to determine the in vitro antibacterial activity of the water-soluble protein enzymatic hydrolysates and the ethanol (EtOH)-extracted fraction obtained from fly-maggots (Musca domestica L.) against MRSA (methicillinresistant Staphylococcus aureus) strains and VRE (Vancomycin-resistant enterococci) 5117 strain. The water soluble protein enzymatic hydroly...

Vancomycin-resistant enterococci (VRE) have become a major concern in medical practice. Asymptomatic VRE colonization of the gastrointestinal tract may lead to infection. In this study, which included patients who stayed in our hospital between 2006 and 2011, we looked at the cases of 342 patients with VRE colonization and 19 patients with VRE infection. Vancomycin and carbapenem exposure and i...

Bloodstream infections due to vancomycinresistant enterococcal species (VRE-BSI) can be a lethal complication for hospitalized patients. VRE-BSI principally affects vulnerable patient populations, including complex postsurgical and internal medicine patients withmultiple comorbid conditions [1–6]. VRE-BSI has particularly high attributable mortality in hematopoietic stem cell transplant recipie...

BACKGROUND The burden and significance of vancomycin-resistant enterococci (VRE) colonization in the ICU is not clearly understood. METHODS We searched PubMed and EMBASE up to May 2013 for studies reporting the prevalence of VRE upon admission to the ICU and performed a meta-analysis to assess rates and trends of VRE colonization. We calculated the prevalence of VRE on admission and the acqui...

Purpose: Multiresistant and vancomycin resistant Enterococcus faecium (VRE) can cause serious infections in hospitalized patients with various co-morbid diseases. We investigated the course of VRE peritonitis after cecal ligation and puncture (CLP)-induced sepsis and compared this to sham operated mice. Methods: Mice were subjected to CLP or sham surgery. Forty-eight hours thereafter four group...

OBJECTIVES To determine the activity of oritavancin against methicillin-resistant staphylococci, vancomycin-resistant enterococci (VRE) and β-haemolytic streptococci recently isolated from acute bacterial skin and skin structure infections or bacteraemia in western Europe. METHODS Forty-one centres in Spain (8), Italy (9), Germany (8), France (8) and the UK (8) submitted 866 isolates [204 met...

The prevalence of vancomycin-resistant enterococci (VRE) colonization or infection in the hospital setting has increased globally. Many previous studies had analysed the risk factors for acquiring VRE, based on cross-sectional studies or prevalent cases. However, the actual incidence of and risk factors for VRE remain unclear. The present study was conducted in order to clarify the incidence of...

Antibiotic resistance is a serious global health problem that poses threat to the successful treatment of various bacterial infections, especially those caused by methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Conventional MRSA VRE infections challenging often requires alternative or combination therapies may have limited efficacy, higher costs, ...

Enterococci have caused infections in hospitalized patients for many decades. Given that they were part of the normal flora of the gastrointestinal (GI) tract and that they frequently appeared as part of the flora in infections related to fecal contamination, they originally were considered endogenous pathogens of little nosocomial import This view began to change with the appearance of enteroc...