نتایج جستجو برای: wake cycle
تعداد نتایج: 293091 فیلتر نتایج به سال:
The human sleep-wake cycle is generated by a circadian process, originating from the suprachiasmatic nuclei, in interaction with a separate oscillatory process: the sleep homeostat. The sleep-wake cycle is normally timed to occur at a specific phase relative to the external cycle of light-dark exposure. It is also timed at a specific phase relative to internal circadian rhythms, such as the pin...
BACKGROUND Alteration of the intensity of light reaching the pineal gland through the visual pathway affects the sleepwake cycle in humans. OBJECTIVE To determine the prevalence, types and severity of sleep-wake disorders in the blind and their relation to the degree and cause of blindness. METHODS One hundred and seventy consecutive blind patients were included in the study. The patients w...
Cognition is regulated across the 24 h sleep-wake cycle by circadian rhythmicity and sleep homeostasis through unknown brain mechanisms. We investigated these mechanisms in a functional magnetic resonance imaging study of executive function using a working memory 3-back task during a normal sleep-wake cycle and during sleep loss. The study population was stratified according to homozygosity for...
In addition to cognitive decline, individuals affected by Alzheimer's disease (AD) can experience important neuropsychiatric symptoms including sleep disturbances. We characterized the sleep-wake cycle in the TgCRND8 mouse model of AD, which overexpresses a mutant human form of amyloid precursor protein resulting in high levels of β-amyloid and plaque formation by 3 months of age. Polysomnograp...
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