kernicterus (bilirubin induced encephalopathy) is an uncommon disorder with tragic consequences, especially when it affects healthy term and near-term neonates. appointment of cut off value of total serum bilirubin level that have a safe margin for early prompt treatment, as a result, prevention of kernicterus. in our study, all of icteric neonates that admitted in our center in 1 year were enr...

objective mercury poisoning is one of the important recent causes of mortality and mortality in children worldwide, particularly in industrial environments; mercury is a poisonous metal, especially harmful to the nervous and immune systems and the kidneys and can even be fatal. elemental mercury is present in thermometers, barometer batteries, sphygmomanometers and latex paints. inorganic mercu...

Objective: To estimate the association of umbilical cord lactate levels and pH with Hypoxic-Ischemic Encephalopathy in neonates born intrapartum asphyxia.
 Study Design: Comparative cross-sectional study.
 Place Duration study: Pediatrics Department, Pak Emirates Military Hospital, Rawalpindi Pakistan, from February 2021 to April 2022.
 Methodology: The study was conducted on sus...

Drug-induced encephalopathy is a disease entity often caused by impaired cerebral metabolism that is not attributed to structural brain lesions. However, some drug-induced encephalopathies can develop structural lesions and share other underlying pathophysiological mechanisms (table 2). Leading symptoms are acute or chronic disturbances of consciousness, brain function and personality changes w...

Hypertensive encephalopathy is an acute neurological syndrome caused by a sudden increase of systemic blood pressure (1, 2). The imaging abnormalities are predominant in the parieto-occipital subcortical white matter. The clinical and radiological abnormalities are reversible after antihypertensive treatment (3). Therefore, hypertensive encephalopathy has been called posterior reversible enceph...

In a nine year necropsy study in Western Australia, the incidence of Wernicke's encephalopathy was 2.8%. The incidence appears to be increasing. Although Wernicke's encephalopathy is a nutritional disorder, the majority of cases occur in the alcoholic population. Only 20% of the 131 cases studied had been diagnosed clinically as Wernicke's encephalopathy. This large discrepancy between numbers ...

BACKGROUND AND PURPOSE White matter abnormalities have been demonstrated to play an important role in minimal hepatic encephalopathy. In this study, we aimed to evaluate whether WM diffusion tensor imaging can be used to identify minimal hepatic encephalopathy among patients with cirrhosis. MATERIALS AND METHODS Our study included 65 patients with cirrhosis with covert hepatic encephalopathy ...

Hashimoto's encephalopathy is a steroid-responsive, relapsing or progressive encephalopathy associated with thyroid autoantibodies. Age at presentation varies from 10 to 78 years. In children, Hashimoto's encephalopathy is rare, and seizures, confusion and hallucinations are the most commonly described features. We report a 10-year-old girl with the diagnosis of Hashimoto's encephalopathy and r...

BACKGROUND AND AIM Hepatic encephalopathy is a frequent complication of cirrhosis. The present retrospective investigation was conducted to characterize metabolic alterations in cirrhotic patients with and without hepatic encephalopathy. We tested the hypothesis that reduced nutritional status or the degree of tissue catabolism are associated with the presence of hepatic encephalopathy. METHO...

Encephalopathy is a disorder characterized by altered brain function, which can be attributed to various causes. Encephalopathy associated with metronidazole administration occurs rarely and depends on the cumulative metronidazole dose, and most patients with this condition recover rapidly after discontinuation of therapy. Because metronidazole is metabolized in the liver and can be transported...