BACKGROUND Blood stream tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB) is common among HIV-positive patients, turning rapidly fatal unless detected and treated promptly. Blood culture is currently the standard test for the detection of MTB in whole blood but results take weeks; patients deteriorate markedly and often die before a diagnosis of blood stream TB is made. Rapid molecu...

abstract background: the invasion of microorganisms into the bloodstream and spread to different parts of body can cause disruption the functions of vital organs and even death. the proper and prompt treatment is essential and can significantly reduce morbidity and mortality rates. this study aimed to determine the frequency and the antimicrobial susceptibility of bacteria isolated from blood c...

neonatal sepsis is an important cause of death and morbidity in newborns and is diagnosed by isolation of organism in blood culture. in several reports,reliablity of blood cultures were done from umbi lical catheters,have been demonstrated. the objective of the present study was to determine,wether an inde welling umbilical catheter, could be an alternative site for blood culture. in a prospect...

BACKGROUND The variation of immune cell activities over time is an immanent property of the human immune system, as can be measured by the stimulated secretion of cytokines in cell cultures. However, inter-individual variability is considerably higher. Especially the latter is the major reason why it has not been possible to establish international standard values for cytokines as was possible ...

BACKGROUND Tuberculosis infection, disease and mortality are all less common at high than low altitude and ascent to high altitude was historically recommended for treatment. The immunological and mycobacterial mechanisms underlying the association between altitude and tuberculosis are unclear. We studied the effects of altitude on mycobacteria and antimycobacterial immunity. METHODS Antimyco...

background: mostly seen toxicities following vancomycin are ototoxicity and nephrotoxicity. we here report a very low birth weight preterm neonate who developed severe episodes of apnea after accidental iatrogenic vancomycin overdose, responsive to treatment with double volume exchange transfusion. case report: a preterm neonate weighing 1380 grams received two doses of 10-fold of the normal do...

conclusions respiratory distress is more common in eos whereas jaundice, fever and seizure are more likely to be observed in los infants. considering the results, clinical manifestations should be regarded as an important part of early diagnosis of sepsis. objectives the aim of this study was to evaluate, record and rank the clinical manifestations and lab data of neonates with clinical sepsis....