Hamster to rat cardiac xenografts undergo delayed rejection as compared with the hyperacute rejection of discordant xenografts. Elicited xenoreactive Abs (EXA) are thought to initiate hamster to rat cardiac xenograft rejection. In this study, we demonstrate that following transplantation of a hamster heart, rats generated high levels of EXA. Adoptive transfer into naive recipients of purified I...

Patient-derived tumor xenograft is the transfer of primary human tumors directly into an immunodeficient mouse. Patient-derived tumor xenograft plays an important role in the development and evaluation of new chemotherapeutic agents. We succeeded in generating a patient-derived tumor xenograft of a biliary tumor obtained by endoscopic ultrasound-guided fine-needle aspiration from a patient who ...

An analysis of 211 patients who had porcine xenograft valve replacements at Henry Ford Hospital between October 1971 and March 1974, was accomplished, with 100% follow-up. The follow-up period extended from 60-89 months after implantation. One hundred sixty-seven patients with 192 valves survived the perioperative period and were subjected to life table analysis. Hemodynamically significant por...

Xenograft models of human cancer play an important role in the screening and evaluation of candidates for new anticancer agents. The models, which are derived from human tumor cell lines and are classified according to the transplant site, such as ectopic xenograft and orthotopic xenograft, are still utilized to evaluate therapeutic efficacy and toxicity. The metastasis model is modified for th...

Objective: The present study aims to use the fractal dimension method assess ossification occurring in patients undergoing an open sinus lift surgery performed with of xenograft. 
 Material and Method: In our study, we used 90 orthopantomographs a total 43 patients. Our consists three groups: Group A, B, C. Using method, assessed taken within six months after (Group A), nine B), more than ...

Feline mammary tumor is a relatively commonly diagnosed neoplasm in the cat. Development of new veterinary cancer therapies limited by shortage vivo models that reproduce microenvironment and metastatic progression. Four feline orthotopic patient-derived xenograft model (PDX) successfully established NOD-SCID gamma (NSG) mice. The overall success rate PDX establishment was 36% (4/11). Histologi...

The aim of this study was to the use tilapia allograft and xenograft in pediatric second-degree burns terms therapeutics clinical-surgical results. This is a narrative literature review carried out through survey articles MEDLINE databases via PubMed, Cochrane Library, VIA ELSEVIER, BVS, LILACS, Scopus. Allograft indicated for covering full-thickness wounds, healing partial-thickness as well pr...

Among the many graft materials that have been used for the treatment of bone defects in oral and maxillofacial regions is xenograft. To improve osteoconductive effects of xenografts, they have been combined with various biocompatible materials, such as hyaluronic acid and bone morphogenetic protein. To determine bone-healing capacity of high molecular weight hyaluronic acid (HA) combined with x...

BACKGROUND Bone tissue engineering requires materials that are biocompatible, mechanically suited for bone function, integrated with the host skeleton, and support osteoinduction of the implanted cells for new bone formation. The aim of this study was to compare the osteogenic potential of xenograft with hydroxyapatite/β- tricalcium phosphate (HA/β-TCP) scaffold. METHODS New Zealand rabbits (...