BACKGROUND Many noninvasive tests exist to determine whether patients should undergo coronary angiography. The routine use of coronary angiography without previous noninvasive testing is typically not advocated. OBJECTIVE To determine the cost-effectiveness of diagnostic strategies for patients with chest pain. DESIGN Cost-effectiveness analysis. DATA SOURCES Published data. TARGET POPU...

Objective: To compare the cost-effectiveness of early laparoscopic choleystectomy (ELC) versus delayed laparoscopic cholecystectomy (DLC) in patients with acute cholecystitis. Design: A decision-tree model was developed using a series that modelled all potential outcomes for both treatment options. Probabilities were estimated from a Cochrane review. Costs were based on the UK National Schedule...

BackgroundWith increasing health care expenditures, knowledge about the benefit and costs of surgical interventions such as total shoulder arthroplasty (TSA) becomes important for orthopedic surgeons, social insurance programs, policy decision makers. We examined impact TSA on quality life (QOL), direct medical costs, productivity losses evaluated cost-utility ratio compared with ongoing nonope...

STUDY DESIGN Longitudinal cohort. OBJECTIVE To determine the cost per quality-adjusted life-year for lumbar epidural steroid injections (LESI). SUMMARY OF BACKGROUND DATA Despite being a widely performed procedure, there are few studies evaluating the cost-effectiveness of LESIs. METHODS Patients who had received LESI between June 2012 and July 2013 with EuroQOL-5D (EQ-5D) scores availabl...

Antiviral treatment of herpes zoster is controversial because of uncertain benefits and relatively high costs. Most studies show that antiviral therapy lessens acute herpes zoster symptoms and postherpetic neuralgia (PHN). Current clinical recommendations support antiviral treatment of severely symptomatic herpes zoster in all adults, and mild herpes zoster in those 50 or 60 years of age or old...

The aim of this study was to estimate monetary value of a QALY among heart disease patients and to identify its determinants.A cross-sectional survey with face-to-face interview was conducted with 196 cardiovascular disease patients from two heart hospitals in Tehran, Iran, to estimate the value of QALY using disaggregated and aggregated approaches. The Euro Qol -5d (EQ-5D) questionnaire, visua...

BACKGROUND In economic evaluation, cost per quality-adjusted life year (QALY) is generally used as an indicator for cost-effectiveness. Although JPY 5 million to 6 million (USD 60, 000 to 75,000) per QALY is frequently referred to as a threshold in Japan, do all QALYs have the same monetary value? METHODS To examine the relationship between severity of health status and monetary value of a QA...

BACKGROUND The aim of this study was to assess the cost-effectiveness of human papillomavirus (HPV) vaccination in addition to the current cervical cancer screening programme in Germany using a dynamic transmission model. METHODS Based on a mathematical model simulating the transmission dynamics and the natural history of HPV infection and associated diseases (cervical intraepithelial neoplas...

OBJECTIVE To compare projected economic costs and health benefits associated with using pneumococcal conjugate heptavalent vaccine as routine immunisation in healthy children in Switzerland. DESIGN A cost-utility analysis was performed from both the societal as well as the sickness funds' perspective. SETTING Simulated birth cohorts of 80,000 children (the approximate size of a birth cohort...