Fusarium is a fungus that is commonly found as saprophytes with parasitic life on some living organisms. Mycoprotein or fungus proteins with physical and chemical features are known as food in recent years. When they are involved in temperature and wet stress, release materials such as mycotoxins or fungus toxins remained in food. Zearalenone and dependent compounds have distinct role in many f...

The BCRP (ABCG2) transporter is responsible for the efflux of chemicals from the placenta to the maternal circulation. Inhibition of BCRP activity could enhance exposure of offspring to environmental chemicals leading to altered reproductive, endocrine, and metabolic development. The purpose of this study was to characterize environmental chemicals as potential substrates and inhibitors of the ...

Each year (2001-2005), 300 samples of wheat from fields of known agronomy were analysed for ten trichothecenes by gas chromatography-mass spectrometry (GC/MS) including deoxynivalenol (DON), nivalenol, 3-acetyl-DON, 15-acetyl-DON, fusarenone X, T2 toxin, HT2 toxin, diacetoxyscirpenol, neosolaniol and T-2 triol and zearalenone by high-performance liquid chromatography (HPLC). Of the eleven mycot...

In the present study, a quantitative dietary exposure assessment of mycotoxins and their masked forms was conducted on a national representative sample of the Belgian population using the contamination data of cereal-based foods. Cereal-based food products (n=174) were analysed for the occurrence of deoxynivalenol, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, zearalenone, α-zearalenol, β-ze...

the contamination of cereals with toxic secondary metabolites of fungi, mycotoxins, is a permanent challenge in human health. these toxins are produced by a few fungi are mainly of the genera fusarium , aspergillus and penicillium . ochratoxin a is a nephrotoxic mycotoxin, which possesses carcinogenic, teratogenic, immunotoxic and possibly neurotoxic properties. zearalenone is a non-steroidal e...

zearalenone (zea) mycotoxin is a potent estrogenic metabolite. it is the primary toxin causing infertility, abortion or other breeding problems. a hplc method was validated for zea in foods using a monolithic column with sample clean-up on an immunoaffinity column. a certified reference material (crm) from fapas (uk) was analyzed. a survey of zea was performed on the 72 samples of rice, bread, ...

Zearalenone (ZEA) is a resorcylic acid lactone derivative produced by various Fusarium species that are widely found in food and feeds. The structure of zearalenone is flexible enough to allow a conformation able to bind to mammalian oestrogen receptors, where it acts as an agonist. Using oestrogen-dependent Human Breast Cancer (MCF-7) cells, the oestrogenic activity of zearalenone and its deri...

introduction: zearalenone is a mycotoxin compound produced mainly by the fusarium species of fungi which is present in several types of foods. t he purpose of this study was to determine the zearalenone in raw animal origin food produced in north-west of iran . materials and methods: from june to december 2012, a total of 210 samples (containing 70 raw milk, 70 meat and 70 liver) were obtained ...

The ability to adsorb zearalenone by five strain of lactic acid bacteria was evaluated: four strains of Lactobacillus spp. isolated from pig rectal swabs and one commercial strain (Lactobacillus rhamnosus). Several factors affecting the adsorption capacity were evaluated in order to improve the adsorption of the mycotoxin by bacteria. The stability of the zearalenone-bacteria complex was analyz...

Genotoxic effects of the mycotoxin Zearalenone (ZEN) were evaluated on albino mice. The investigation was assessed using 4 criteria: chromosome aberrations in bone marrow and spermatocytes of adult male mice; chromosome analysis and teratological effects of mice embryos. Zearalenone was administrated to both adult males and pregnant females with 2 doses level (5 microg x kg(-1) and 10 microg x ...