The fresh rhizome of Zingiber zerumbet Smith (Zingiberaceae) is used as a food flavoring and also serves as a folk medicine as an antipyretic and for analgesics in Taiwan. Zerumbone, a monocyclic sesquiterpene was isolated from the rhizome of Z. zerumbet and is the major active compound. In this study, the anti-inflammatory and antinociceptive effects of zerumbone on arthritis were explored usi...

The control of fish disease is mostly based on synthetic antimicrobial agents. Indiscriminate usage agents has resulted in antibiotics resistance. Therefore, the present study aims to evaluate potential properties herbal plants as an alternative agent. susceptibility pathogens namely Bacillus sp., Enterococcus faecalis, Staphylococcus aureus, Streptococcus agalactiae, Aeromonas hydrophila, Esch...

BACKGROUND The extraction of bioactive compounds from herbal materials requires optimization in order to recover the highest active dose. Response surface methodology was used to optimize variables affecting the microwave extraction of zerumbone from Zingiber zerumbet using the Box-Behnken design. The influence of variables, such as ethanol concentration (X1), microwave power (X2), irradiation ...

OBJECTIVE The present study was carried out to determine the antiinflammatory and antinociceptive activities of a methanol extract of Zingiber zerumbet rhizomes (MEZZ) using various experimental model systems. MATERIALS AND METHODS The MEZZ was prepared by macerating oven-dried (50 degrees C) powdered rhizomes (1.2 kg) of Z. zerumbet in 80% methanol in a ratio of 1:20 (w/v) for 48 h. The supe...

Over the past eight decades, numerous research has been conducted on extraction of Zingiber zerumbet rhizome. The mini-review includes information pharmacological properties zerumbone extracted from Z. rhizome and methods over previous 80 years. Zerumbone is recognised as having a proven effect significant medicinal component used to treat various ailments. values are stated based findings. met...

Zerumbone, the key constituent of Zingiber zerumbet Smith, is a very important bioactive phytochemical. Two new compounds viz. azazerumbone 1 and azazerumbone 2 were synthesised by ZnCl2-catalysed Beckmann rearrangement of the zerumbone oxime. The structure elucidation of these analogues of zerumbone was carried out by 1D ((1)H NMR and (13)C NMR) and 2D-NMR (COSY, HSQC and NOESY) spectral analy...