BACKGROUND The frequency of defective sperm-zona pellucida (ZP) interaction in teratozoospermic infertile men was investigated. METHODS Sperm-ZP binding and the ZP-induced acrosome reaction (ZPIAR) were performed in 125 infertile men with <5% of their sperm with normal morphology (strict criteria), but with a sperm count > or =20x10(6)/ml and total motility >30% in semen. Oocytes that failed ...

The main result of [7] was that if M is a simply-connected four-manifold admitting an effective, homologically trivial, locally linear action byG = Zp×Zp, where p is prime, then M is equivariantly homeomorphic to a connected sum of standard actions on copies of ±CP 2 and S2 × S2 with a possibly non-standard action on S4. In this note we further examine these non-standard actions on the sphere. ...

Recently, zero-padding orthogonal frequency division multiplexing (ZP-OFDM) has been proposed as an alternative solution to the traditional cyclic prefix (CP)-OFDM, to ensure symbol recovery regardless of channels nulls. Various ZP-OFDM receivers have been proposed in the literature, trading off performance with complexity. In this paper, we propose a novel low-complexity (LC) receiver for ZP-O...

Sperm-zona pellucida (ZP) binding is the first step of gamete interaction. This binding occurs in two sequential steps, starting with the primary binding of acrosome-intact sperm to the ZP followed by the secondary ZP binding of acrosome reacting/reacted sperm. While there are only a few ZP sulfoglycoproteins involved in these binding events, a large number of sperm surface molecules have been ...

Abbreviations: ZP, zona pellucida; ZPG, ZP glycoprotein; VE, vitelline envelope; VEG, VE glycoprotein; mZP, mouse ZP; hZP, human ZP; SS, signal sequence; CTP, C-terminal propeptide; CFCS, consensus furin cleavage-site; TMD, transmembrane domain; ZPD, ZP domain; NTS, N-terminal subdomain; CTS, C-terminal subdomain; EHP, external hydrophobic patch; IHP, internal hydrophobic patch; CP, charged pat...

We report the characterization of the zebrafish zp-50 class III POU domain gene. This gene is first activated in the prospective diencephalon after the end of the gastrula period. During somitogenesis, zp-50 is expressed in a very dynamic and complex fashion in all major subdivisions of the central nervous system. After one day of development, zp-50 transcripts are present in the fore- and midb...

Zaleplon (ZP) is a sedative and hypnotic drug used for the treatment of insomnia. Despite its potent anticonvulsant activity, ZP not commonly convulsion since characterized by low oral bioavailability as result poor solubility extensive liver metabolism. The following study aimed to formulate specifically controlled release nano-vehicles parenteral delivery enhance biological activity. A modifi...

0.1. Let X be a scheme, reduced and separated, of finite type over Z. For p a prime number, one may consider the set X(Zp) of its Zp-rational points. For every n in N, there is a natural map πn : X(Zp)→ X(Z/p) assigning to a Zp-rational point its class modulo p. The image Yn,p of X(Zp) by πn is exactly the set of Z/p-rational points which can be lifted to Zp-rational points. Denote by Nn,p the ...

Many investigators maintain that spermatozoa that have initiated the acrosome reaction (AR) before reaching the surface of the egg's zona pellucida (ZP) are unable to bind and penetrate the ZP. A recent study has revealed that most fertilizing mouse spermatozoa initiate the AR before contacting the ZP. We found that acrosome-reacted spermatozoa collected from the perivitelline space of Cd9-null...

Seventy-two bacterial strains were isolated from twenty various sources including soil, water, rotten fruits, vegetables etc. Preliminary screening for pectinase producing bacterial strains was done by well plate method and twenty-six bacterial strains gave zones on Minimum Salt (MS) medium supplemented with 0.2% pectin. Most of the isolates belonged to plant origin, either rotten fruits or veg...