Anthocyanins are naturally occurring water-soluble plant pigments belonging to the flavonoids chemical class. The red, blue and purple colours of leaves, flowers fruits plants confirm that they rich sources anthocyanins. Many in vivo vitro studies reveal anthocyanins have different health beneficial effects such as antioxidant, antidiabetic, anti-inflammatory, anti-obesity, antihypertensive ant...

Abstract As a gaseous mediator, hydrogen sulfide (H 2 S) has many physiological effects and pathological in atherosclerosis. In recent years, exogenous H S donors have been synthesized to study atherosclerosis diseases. this study, proglumide-(5-(4-hydroxyphenyl)-3 -1,2-dithiole-3-thione) (P-A) was as donor. The protective effect mechanism of P-A on HUVEC that injured by ox-LDL were detected. H...

Background: Human neutrophil peptide-1 (HNP-1) is a commonly investigated therapeutic agent. However, its role in hypertensive left ventricular hypertrophy (HLVH) remains unclear. Methods: We measured HNP-1 levels patients with hypertension and treated HLVH rat H9c2 cell models HNP-1. Cardiomyocyte indexes (i.e., single-cell surface area, fibrosis BNP levels, β-MHC levels) were hematoxylin-eosi...

Apoptosis is a programmed cellular process that occurs in pathological and physiological pathways it one of the most studied topics cell biology. To understand underlying mechanism apoptosis plays an important role molecular pathogenesis many diseases including cancers. Chronic myeloid leukemia (CML) clonal myeloproliferative malignancy arising from neoplastic transformation hematopoietic stem ...

It is well-known that cancer therapies, including chemotherapy drugs, aromatase inhibitors and gonadotropin-releasing homone analogues, commonly contribute to remarkably reduce the bone mineral density, subsequently increase rate of loss. For instance, in patients with prostate treated androgene deprivation therapy (ADT), or drugs such as doxorubicin cisplatin calcicum levels were significantly...