Background: Diabetes is the most common cause of kidney disease in people requiring renal replacement therapy (RRT). RRT projected to dramatically increase globally, with greatest Asia. CREDENCE showed canagliflozin reduces and cardiovascular (CV) events individuals type 2 diabetes (T2DM) chronic (CKD).Methods: We explored efficacy across geographic regions. A Cox proportional-hazards model was...

Right ventricular (RV) dysfunction due to post-capillary pulmonary hypertension is a common sequela of elevated left (LV) filling pressures in patients with heart failure (HF) which has been demonstrated be associated poor clinical outcomes.1-3 Measures RV–pulmonary artery (RV-PA) coupling that evaluate indices RV function and severity have shown outcomes.4, 5 A phase 2 trial, COSMIC-HF (Chroni...

Рисование и рассматривание изображений тесно связаны с воображением, фундаментальной характеристикой человеческого интеллекта. Прогресс цифровой техники сегодня делает возможным производство техногенных изображений, но обнаруживается, что здесь все равно нужен какой-то опыт обычного рисования, вдобавок необходимо обладать еще философским пониманием обстоятельств, приводящих к фигуре «человека р...

cognitive mode. Indeed Socrates asserts that as the levels of cognition are ascended, with the character of "clearness" and "precision," so do their objects "...partake of truth and reality." Unfortunately, just as the "Good" itself was left unexplained as a causal principle in the sun eikon, so is that unhypothetical first principle also left unexplained here, in the divided line. Most importa...