BACKGROUND Legg-Calve-Perthes Disease (LCPD) is an idiopathic osteonecrosis of the developing femoral head complicated by pain and disability of the hip joint. To date, the pathological mechanisms of LCPD are not well-known. This study screened the changes in serum protein expression in patients with LCPD. METHODS Age- and sex-matched serum samples from 10 control subjects and 10 patients wit...

Legg-Calve-Perthes disease (LCPD) is a degenerative condition of the hip joint characterised by idiopathic avascular necrosis of the femoral head. Loss of bone mass causes a degree of collapse of the joint and may result in deformity of the ball of the femur and the surface of the hip socket. A reduction in hip joint range of motion, alternation in growth of femoral head, and associated pain ar...

OBJECTIVES The objective of this study was to investigate cases of femoroacetabular impingement (FAI) and analyze the risk factors for a painful hip at skeletal maturity after Perthes disease. We hypothesized that FAI occurs as a sequela of Perthes disease and that coxa plana and triple osteotomy of the pelvis (TOP) may be risk factors. METHODS Ninety-five hips were included from 1981 to 2011...

Synonyms for this disease include “avascular necrosis of the femoral head” and “aseptic necrosis of the femoral head”, “Perthes disease” and “Legg Perthes” disease, “osteochon-dritis”, “coxae juvenilis”, “coxa plana” and “idiopathic osteosis”. The terms “avascular/aseptic necrosis of the femoral head” are also used to describe a process of femoral head necro-sis in dogs following traumatic frac...

BACKGROUND Legg-Calve´-Perthes disease is a juvenile idiopathic osteonecrosis in which the blood supply of femoral head is not sufficient and the bone dies provisionally. The aim of this study is to evaluate outcome of Femoral osteotomy in children with LCPD in our University Hospital. METHODS In a descriptive analytic study, between 2008 and 2013, patients with the diagnosis of Legg-Calve'-P...

Legg-Perthes disease (osteochondritis deformans) is an aseptic necrosis of the capital femoral epiphysis. The clinical and radiographic features of Legg-Perthes disease have been well documented (Goff, Shutkin, and Hersey, 1954; Kemp and Boldero, 1966) but apart from Molloy and MacMahon's Massachusetts study (1966) few epidemiologic investigations have been reported. A genetic component to the ...