The generic classification of the ant subfamily Dorylinae is revised, with the aim of facilitating identification of easily-diagnosable monophyletic genera. The new classification is based on recent molecular phylogenetic evidence and a critical reappraisal of doryline morphology. New keys and diagnoses based on workers and males are provided, along with reviews of natural history and phylogene...

Alpha-synuclein (α-Syn) aggregates are the main component of Lewy bodies, which are the characteristic pathological feature in Parkinson's disease (PD) brain. Evidence that α-Syn aggregation can be propagated between neurones has led to the suggestion that this mechanism is responsible for the stepwise progression of PD pathology. Decreasing α-Syn expression is predicted to attenuate this proce...

The proposal in this document is Experimental. While it may be deployed in the current Internet, it does not represent a consensus that this is the best possible mechanism for the use of Explicit Congestion Notification (ECN) in TCP SYN/ACK packets. This document describes an optional, experimental modification to RFC 3168 to allow TCP SYN/ACK packets to be ECN-Capable. For TCP, RFC 3168 specif...

Parkinson’s disease (PD) is a movement disorder characterized by the appearance of inclusions known as Lewy bodies, most prominently in the substantia nigra pars compacta. The synaptic protein α-synuclein (α-syn) and polyubiquitin are major components of Lewy bodies. The objective of this study was, firstly, to evaluate whether α-syn inhibits proteolytic function of the proteasome and, secondly...

Synucleins (Syn), a family of synaptic proteins, includes alpha-Syn, which plays a pivotal role in Parkinson's disease and related neurodegenerative diseases (synucleinopathies) by forming distinct brain pathologies (Lewy bodies and neurites). Since traumatic brain injury (TBI) is a poorly understood risk factor for Parkinson's disease, we examined the effects of TBI in the young and aged mouse...

This draft specifies a modification to RFC 3168 to allow TCP SYN/ACK packets to be ECN-Capable. For TCP, RFC 3168 only specifies setting an ECN-Capable codepoint on data packets, and not on SYN and SYN/ACK packets. However, because of the high cost to the TCP transfer of having a SYN/ACK packet dropped, with the resulting retransmit timeout, this document specifies the use of ECN for the SYN/AC...

Crematogaster ants are diverse, widespread and abundant in tropical, subtropical and warm-temperate climates throughout the world. The species diversity of this genus has been notoriously difficult to manage based upon morphology alone, and former attempts have generated a vaguely defined subgeneric system. I propose an improvement of the previous subgeneric classification and recognize two sub...

Nine 5-bromodeoxyuridine-induced temperature-sensitive (ts) mutants were isolated from stocks of a syncytial plaque type mutant (syn) itself derived from the non-syncytial wild-type (syn +) of the GLASGOW strain i7 of herpes simplex virus type i. The nine ts mutants have been assigned to eight cistrons on the basis of different complementation tests. Non-syncytial revertants isolated from the o...

Abnormal folding of -synuclein ( -syn) is thought to lead to neurodegeneration and the characteristic symptoms of Lewy body disease (LBD). Since previous studies suggest that immunization might be a potential therapy for Alzheimer’s disease, we hypothesized that immunization with human (h) -syn might have therapeutic effects in LBD. For this purpose, h syn transgenic (tg) mice were vaccinated w...

The proposal in this document is Experimental. While it may be deployed in the current Internet, it does not represent a consensus that this is the best possible mechanism for the use of Explicit Congestion Notification (ECN) in TCP SYN/ACK packets. This document describes an optional, experimental modification to RFC 3168 to allow TCP SYN/ACK packets to be ECN-Capable. For TCP, RFC 3168 specif...