نتایج جستجو برای: روش nasba

تعداد نتایج: 369774  

Journal: :iranian journal of biotechnology 2008
alireza saeedinia mehdi shamsara mehdi zeinoddini vahid sadeghi nader maghsoudi

enteroviruses are the causative agents of a number of diseases in humans. group b coxsackieviruses are believed to be the most common viral agents responsible for human heart disease. genomic data of enteroviruses has allowed developing new molecular approaches such as nucleic acid sequence based amplification (nasba) for detection of such viruses. in this study, coxsackievirus b3 (cvb3) was de...

Journal: :Journal of clinical microbiology 2009
Claire M Mugasa Thierry Laurent Gerard J Schoone Piet A Kager George W Lubega Henk D F H Schallig

Molecular tools, such as real-time nucleic acid sequence-based amplification (NASBA) and PCR, have been developed to detect Trypanosoma brucei parasites in blood for the diagnosis of human African trypanosomiasis (HAT). Despite good sensitivity, these techniques are not implemented in HAT control programs due to the high cost of the equipment, which is unaffordable for laboratories in developin...

2010
Alfarazdeg A. Saad Nuha G. Ahmed Osman S. Osman Ahmed Almustafa Al-Basheer Awad Hamad Stijn Deborggraeve Philippe Büscher Gerard J. Schoone Henk D. Schallig Thierry Laurent Ahmed Haleem Omran F. Osman Ahmed Mohamedain Eltom Mustafa I. Elbashir Sayda El-Safi

BACKGROUND The Leishmania OligoC-TesT and NASBA-Oligochromatography (OC) were recently developed for simplified and standardised molecular detection of Leishmania parasites in clinical specimens. We here present the phase II evaluation of both tests for diagnosis of visceral leishmaniasis (VL), cutaneous leishmaniasis (CL) and post kala-azar dermal leishmaniasis (PKDL) in Sudan. METHODOLOGY T...

فروزنده مقدم, مهدی, محمدی یگانه, سمیرا, پریان, مهدی ,

  چکید ه   سابقه و هدف   هپاتیت C ، شایع‌ترین بیماری ویروسی قابل انتقال از طریق خون، در میان معتادان تزریقی می‌باشد. در مطالعه حاضر یک روش تکثیر اسید نوکلئیک هم‌دما (NASBA) در ترکیب با روش Real-time بر اساس پروب Molecular Beacon برای ردیابی ویروس HCV مورد استفاده قرار گرفت.   مواد و روش‌ها   در یک مطالعه تجربی، طراحی جفت آغازگر و پروب برای ناحیه حفاظت شده 5'NCR ویروس HCV به طول bp 241 با نرم‌اف...

Journal: :BioTechniques 1998
N Chadwick A J Wakefield R E Pounder I J Bruce

DNA products generated from a region of the measles virus genome by three RNA reverse transcription and amplification methods were cloned and sequenced, and the results were compared in order to evaluate the methods' relative fidelities. The methods were: (i) reverse transcription followed by a nested polymerase chain reaction (RT-nPCR), (ii) a combined RT-PCR using rTth polymerase and (iii) nu...

Journal: :Applied and environmental microbiology 2001
J Jean B Blais A Darveau I Fliss

A nucleic acid sequence-based amplification (NASBA) technique for the detection of hepatitis A virus (HAV) in foods was developed and compared to the traditional reverse transcription (RT)-PCR technique. Oligonucleotide primers targeting the VP1 and VP2 genes encoding the major HAV capsid proteins were used for the amplification of viral RNA in an isothermal process resulting in the accumulatio...

Viral myocarditis is a moderate disease, but it sometimes causes progressive cardiac disorder. Many different viruses have been considered as the agent of viral myocarditis, but Coxsackievirus of the B group, in particular of the Coxsackievirus B3 (CVB3), is more than fifty percent of cases of viral myocarditis. CVB3 is a positive single-stranded RNA virus and a member of the genus Enterovirus ...

Journal: :Journal of virological methods 2010
Lok Ting Lau Xiao Yan Feng Tsz Yan Lam Hung Kit Hui Albert Cheung Hoi Yu

A group of common lower respiratory tract infections, influenza A, influenza B, human parainfluenza virus 1-4 (HPIV1-4), respiratory syncytial virus (RSV), rubella virus (RV) and Coxsackie virus (CSV), were selected for the development of a multiplex nucleic acid sequence-based amplification (NASBA) assay. Quantifiable measurement utilizing an enzyme-linked oligonucleotide capture (EOC) optical...

Journal: :Tropical medicine & international health : TM & IH 2010
Frank L Basiye Margaret Mbuchi Charles Magiri George Kirigi Stijn Deborggraeve Gerard J Schoone Alfarazdeg A Saad Sayda El-Safi Enock Matovu Monique K Wasunna

OBJECTIVE To estimate the sensitivity and specificity of the OligoC-TesT and nucleic acid sequence-based amplification coupled to oligochromatography (NASBA-OC) for molecular detection of Leishmania in blood from patients with confirmed visceral leishmaniasis (VL) and healthy endemic controls from Kenya. METHODS Blood specimens of 84 patients with confirmed VL and 98 endemic healthy controls ...

ژورنال: :فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران 0
علی ناظمی ali nazemi student of phd of molecular genetics, department of biology, islamic azad university, science and research campus, tehran, iran مجید صادقی زاده majid sadeghizadeh associate professor, department of genetics, tarbiat modarres university, tehran, iran مهدی فروزنده مقدم mehdi forouzandeh moghaddam associate professor, department of medical biotechnology, tarbiat modarres university, tehran, iran غلامرضا جوادی gholamreza javadi associate professor, department of biology, islamic azad university, science and research campus, tehran, iran مهرداد هاشمی mehrdad hashemi assistant professor,department of molecular genetics, islamic azad university, tehran medical branch, tehran, iran علی محمد اصغریان ali mohammad asgharian phd student of cell and molecular biology, department of biology, islamic azad university, science and research branch, tehran, iran

سابقه و هدف: بیماران مبتلا به لوسمی میلوئیدی مزمن (cml) دارای کرموزوم فیلادلفیا هستند. این کروموزوم حاصل جابجایی بازوهای بلند کروموزوم های 9 و 22 (q34q11) بوده که منجر به ایجاد الحاق بین ژنهای bcr و abl می گردد. در این مطالعه، تکنیک های rt-pcr و nasba در تعیین رونویس های bcr-abl مقایسه شد.روش بررسی: رونویس های الحاقی بطور مصنوعی سنتز و rna از رده سلولی لوسمیک k562 استخراج گردید. سریال رقت هم از...

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