A recognition site for benzodiazepines structurally different from that linked to the gamma-aminobutyric acid receptor subtype A or the "central type" benzodiazepine receptor has been located mainly in the outer membranes of mitochondria and designated mitochondrial benzodiazepine receptor (MBR). A putative endogenous ligand for MBR is the peptide, diazepam binding inhibitor (DBI), which inhibi...

The distribution of the sequence of ranked maximum and minimum values attained during excursions of a standard Brownian bridge Bbr t 0 ≤ t ≤ 1 is described. The height Mbr+ j of the jth highest maximum over a positive excursion of the bridge has the same distribution as Mbr+ 1 /j, where the distribution of Mbr+ 1 = sup0≤t≤1 Bbr t is given by Lévy’s formula P Mbr+ 1 > x = e−2x 2 . The probabilit...

Background B-cell lymphomas harboring the 8q24/MYC plus 18q21/BCL2 translocations are now referred to as high grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-MBR). Although HGBL-MBR is frequently found in cases with diffuse large B-cell lymphoma or Burkitt lymphoma-like B-cell lymphoma, acute lymphoblastic leukemia (ALL)-like disease of HGBL-MBR (AL-HGBL-MBR) has been r...

The most effective soil fumigant for the past 40 years for preplant chemical control of nematodes, weeds, and fungal pathogens in Florida vegetable production has been methyl bromide (MBr). Unfortunately, MBr has been implicated in depletion of stratospheric ozone, and is slated to be banned in the United States. A possible alternative replacement to MBr is metam sodium (MS, sodium N-methyl dit...

A novel quorum quenching (QQ) strain, Acinetobacter guillouiae ST01, was isolated from a full-scale membrane bioreactor (MBR) and characterized for its QQ activities. Batch reactor studies at lab-scale showed that A. ST01 exhibited higher activity against acyl homoserine lactones (AHLs) with an oxo group compared to those without group. The organism then inoculated (10%) in MBR (Q-MBR) treating...

The removal of trace organics by a membrane bioreactor-granular activated carbon (MBR-GAC) integrated system were investigated. The results confirmed that MBR treatment can be effective for the removal of hydrophobic (log D>3.2) and readily biodegradable trace organics. The data also highlighted the limitation of MBR in removing hydrophilic and persistent compounds (e.g. carbamazepine, diclofen...

Purpose. To determine the correlations among the mean blur rate (MBR) in the optic nerve head (ONH) shown by laser speckle flowgraphy (LSFG), retinal arteriosclerosis, and the circulation time obtained by fluorescein angiography (FA). Method. We evaluated 118 patients and assessed their time of choroidal flush, arm-to-retina time, and early and late phases of retinal circulation time (RT: sec) ...

Although membrane bioreactor (MBR) systems provide better removal of pathogens compared to conventional activated sludge processes, they do not achieve total log removal. The present study examines two MBR systems treating municipal wastewater, one a full-scale MBR plant and the other a lab-scale anaerobic MBR. Both of these systems were operated using microfiltration (MF) polymeric membranes. ...

Modern automatic speech recognition (ASR) systems use statistical models of spoken language. These models are typically learned from corpora comprising many hours of transcribed speech. While a variety of machine learning approaches have been applied to this learning task, the optimal learning strategy is unknown. This thesis focusses upon a relatively recent and successful approach, the applic...