Housing, Mobility and Unemployment ∗ This paper develops a model that shows why high-skilled workers move more and are therefore unemployed less than low-skilled workers. The model can explain the paradoxical empirical regularity that higher owner-occupation rates are associated with higher levels of unemployment although home-owners tend to be unemployed less. The choice of housing tenure affe...

BACKGROUND In this study, we investigated the functional correlation between microRNA-210 (miR-210) and gene of F-box protein 31 (FBXO31) in regulating breast cancer. METHODS Dual-luciferase assay and quantitative real-time polymerase chain reaction were used to investigate the binding of miR-210 with FBXO31 and their expression patterns in breast cancer. miR-210 was inhibited in breast cance...

Cerebral edema, primarily caused by disruption of the blood-brain barrier (BBB), is one of the serious complications associated with brain injury in neonatal hypoxic-ischemic encephalopathy (HIE). Our recent study demonstrated that the hypoxic-ischemic (HI) treatment significantly increased microRNA-210 (miR-210) in the neonatal rat brain and inhibition of miR-210 provided neuroprotection in ne...

Hyperlipidemia, including the oxidized low-density lipoprotein (oxLDL) accumulation, is a risk and highly associated with the development of cancers and cardiovascular diseases. microRNA-210 (miR-210), a hypoxia-responsive microRNA regulated by HIF-1α, has been implicated in cancer and cardiovascular disease formation. Furthermore, Bioinformatics analysis revealed that the promoter of the miR-2...

Most metazoan microRNA (miRNA) target sites have perfect pairing to the "seed" sequence, a highly conserved region centering on miRNA nucleotides 2-7. Thus, complementarity to this region is a necessary requirement for target prediction algorithms. However, also non-canonical miRNA binding can confer target regulation. Here, we identified a seedless target of miR-210, a master miRNA of the hypo...

In lab-scale experiments at the 2-stage activated sludge pilot plant of Vienna’s central WWTP it is shown that the wastewater soluble COD concentration, which is inert to a sludge with SRT < 1 d (SIA) is about double compared to the SI concentration in sludge with SRT > 10 d (SIB). Unexpectedly the ratio of SIA/SIB is independent of the sludge age between SRTs of 0.4 and 1.0 days. The differenc...

Obesity can be defi ned as a chronic disease with serious impact on an individual’s quality of life, but moreover, it is a leading risk factor for global death. Bariatric surgery has already proven its effi cacy in rendering the patient a healthier life. Nonetheless, failure of an initiated treatment is possible in medical practice. We can and should offer our patients a correct revisional pati...