Cannabinoids, the primary active agent in drugs of abuse such as marijuana and hashish, tend to generate a distorted sense of time. Here we study the effect of cannabinoids on the brain's circadian clock, the suprachiasmatic nucleus (SCN), using patch clamp and cell-attached electrophysiological recordings, RT-PCR, immunocytochemistry, and behavioral analysis. The SCN showed strong expression o...

EACH YEAR, MORE THAN 730 000 Americans experience a new or recurrent stroke, with resulting direct and indirect health care costs totaling $35 billion and $21.8 billion, respectively. Up to 85% of the approximately 566 000 stroke survivors experience hemiparesis, resulting in impairment of an upper extremity immediately after stroke, and between 55% and 75% of survivors continue to experience u...

Introduction: One of the clinical problems in orthodontics is the bonding of brackets tocomposite restorations. The aim of this study was to evaluate the shear bondstrength of brackets bonded to composite restorations using Excite. Methods:Forty brackets were bonded to composite surfaces, which were embedded inacrylic resin. One of the following four protocols was employed for surfacepreparatio...

abstract introduction: the mineral content of dentin increases with age and its primary structure is altered. these changes may have unknown effects on efficiency of adhesive systems. the aim of this study was to find the effect of aging on dentin bonding agents. methods and materials: fourty eight extracted human premolars were divided into 2 groups under 15 years old & 2 groups over 45 years ...

برای دستیابی به مزیت رقابتی در شرایط عدم‌­اطمینان که آن تغییر ضروری است، یکی از چالش‌های بزرگ سازمان‌ها کاهش ریسک طریق ایجاد زنجیره‌های تأمین تاب‌آور است. تاب‌آوری زنجیره ‌تأمین توانایی مقابله با اختلال اشاره دارد یک رویداد غیرقابل‌پیش‌بینی بوده و دارای منابع داخلی خارجی مختلفی ازجمله بلایای طبیعی ریسک‌های عملیاتی پژوهش حاضر شبیه‌سازی توسط نرم‌افزار ارنا زنجیره‌ سنگ ساختمانی «کارخانه سنگبری آسم...