introduction: an ideal intracanal medicament should be able to eliminate any remaining intracanal microorganism. the aim of this study was to compare the antimicrobial effects of bioglass 45s5 with calcium hydroxide on enterococcus ( e ) faecalis in-vitro . materials & methods: direct exposure test (det) was used to evaluate the antimicrobial effect of bioglass 45s5, calcium hydroxide and norma...

objective: bioactive glass 45s5 is a surface reactive glass-ceramic biomaterial, developed in 1969. bag 45s5 with particle size of 20-60 nm has the ability of bone regeneration, broad spectrum antibacterial effect, repairs and replaces diseased or damaged bone. the aim of this study was to evaluate the antibacterial activity and determine mic and mbc values of nano-bag45s5 on streptococcus muta...

in order to increase the life span of implants, coatings such as bioglass are applied on implants' surfaces to prevent their corrosion in biological fluids. in this research, 45s5 bioglass coatings were applied on 316l stainless steel substrate by sol- gel method and coating's properties were examined by different analyses. according to the xrd results, an amorphous compound containing na2ca2si...

Abstract Bioglass 45S5 is the most widely used bioactive glass composition in orthopedics to regenerate bone tissue. Although its reactions vitro and vivo are well established, impact of local environment on dissolution behavior dynamic not fully understood. Here, we show that ion concentrations released from into Tris‐buffer solution simulated body fluid (SBF) a cascade system three reactors s...

This study aimed to investigate bone responses to a novel bioactive fully crystallized glass-ceramic of the quaternary system P(2)O(5)-Na(2)O-CaO-SiO(2) (Biosilicate®). Although a previous study demonstrated positive effects of Biosilicate® on in vitro bone-like matrix formation, its in vivo effect was not studied yet. Male Wistar rats (n = 40) with tibial defects were used. Four experimental g...

Sol–gel synthesis of BG 45S5 using organic acetic acid as a catalyst was found to be superior the conventional inorganic method.

Ideally, bioactive ceramics for use in alveolar ridge augmentation should possess the ability to activate bone formation and, thus, cause the differentiation of osteoprogenitor cells into osteoblasts at their surfaces. Therefore, in order to evaluate the osteogenic potential of novel bone substitute materials, it is important to examine their effect on osteoblastic differentiation. This study e...

Melt quenched silicate glasses containing calcium, phosphorus and alkali metals have the ability to promote bone regeneration and to fuse to living bone. Of these glasses 45S5 Bioglass® is the most widely used being sold in over 35 countries as a bone graft product for medical and dental applications; particulate 45S5 is also incorporated into toothpastes to help remineralize the surface of tee...