The present work describes a simple Reverse Phase HPLC method for the determination of Omeprazole and Domperidone from capsule formulations. The determination was carried out on a Gasco, ODS, C-18 (250× 4.5 mm, 5 micron) column using a mobile phase of Acetonitrile: 0.05M ammonium acetate buffer (pH4) in the ratio of (85:15). The flow rate and runtime were 1 ml/min and 10 min, respectively. The ...

Ambulatory oesophageal pH, oesophageal manometry and fasting serum gastrin concentrations were carried out on 28 patients with reflux oesophagitis, before and during treatment with ranitidine 300 mg bd. Fourteen patients healed endoscopically at six weeks (group A) and 14 had residual oesophagitis (group B). Group A were characterised by a lower serum gastrin concentration before treatment (4.5...

This paper presents an investigation on titanium dioxide (TiO2) and zinc oxide (ZnO) bilayer film, which is used as sensing membrane for extended-gate field effect transistor (EGFET) for pH sensing application. TiO2/ZnO thin films were deposited using sol-gel spin coating method on indium tin oxide (ITO) substrates. After the deposition, the bilayer films were annealed at constant temperatures ...

The increase in new cases of drug resistance to first-line drugs such as ethambutol (ETB) makes it necessary develop improvements for antituberculosis drugs. A method improving the bioavailability active pharmaceutical ingredient (API) was investigated preventing and side-effects In this study, an delivery system using β-cyclodextrin (β-CD) supramolecular carrier ETB prepared kneading method. i...