[ANTONIO] ALIOTTA, The idealistic reaction against science, [facsimile of 1914 ed.], New York, Arno Press, 1976, 8vo, pp. xxii, 483, $28.00 JOHN R. BAKER, Thefreedom ofscience, [facsimiles of The scientific life (1943), and Science and the planned state (1945)], New York, Arno Press, 1975, 8vo, pp. 154, 120, $15.00. [ROBERT] FLINT, Philosophy as scientia scientiarum and a history of classificat...

I met Arno Locks in the 80s when he was my undergraduate professor. However, he will always be my professor; not only in Orthodontics, but also in ethics and fight for the causes of Dentistry. He loves what he does. And those who love, also care, listen and get involved. As undergraduate students, we were aware that a forward-thinking professional who devoted special attention to his students w...

Podosomes represent a class of integrin-mediated cell-matrix adhesions formed by migrating and matrix-degrading cells. We demonstrate that in macrophage-like THP1 cells and fibroblasts stimulated to produce podosomes, down-regulation of the G-protein ARF1 or the ARF1 guanine nucleotide exchange factor, ARNO, by small, interfering RNA or pharmacological inhibitors led to striking podosome elimin...

[ANTONIO] ALIOTTA, The idealistic reaction against science, [facsimile of 1914 ed.], New York, Arno Press, 1976, 8vo, pp. xxii, 483, $28.00 JOHN R. BAKER, Thefreedom ofscience, [facsimiles of The scientific life (1943), and Science and the planned state (1945)], New York, Arno Press, 1975, 8vo, pp. 154, 120, $15.00. [ROBERT] FLINT, Philosophy as scientia scientiarum and a history of classificat...

این پژوهش با الهام گرفتن از نتایج یک طرح مطالعاتی کاربردی، رویکرد سلسله­‌مراتبی جهت پیگیری فرایند توسعه تأمین‌کنندگان و حمایت تصمیمات موجود در هر مراحل آن ارائه‌ می‌کند. ابتدا، زمینه‌های تأمین نیازمند سپس واجد شرایط هریک زمینه‌ها به کمک تصمیم‌گیری چندشاخصه بهترین-بدترین مشخص می‌گردند. معیارهای شناسایی نیز مرور مطالعات پیشین بهره‌گیری نظرات خبرگان حوزه‌ی خرید استخراج‌شده‌اند. درنهایت، مدل ریاضی ...

To establish pathogenicity, bacteria must evade phagocytosis directed by remodeling of the actin cytoskeleton. We show that macrophages facilitate pathogen phagocytosis through actin polymerization mediated by the WAVE regulatory complex (WRC), small GTPases Arf and Rac1, and the Arf1 activator ARNO. To establish extracellular infections, enteropathogenic (EPEC) and enterohaemorrhagic (EHEC) Es...