Glioblastoma multiform (GBM) remains clinical indication with significant "unmet medical need". Innovative new therapy to eliminate residual tumor cells and prevent tumor recurrences is critically needed for this deadly disease. A major challenge of GBM research has been the identification of novel molecular therapeutic targets and accurate diagnostic/prognostic biomarkers. Many of the current ...

The paper addresses the problem of sustainability assessment of territorial transformations making use of the ANP. Particularly, the case of a new transport infrastructure in a city located in Northern Italy has been considered in the work. The project refers to the implementation of the ring road of the city which will lead to a radically new multifunctional design of the urban area. In the ap...

With globalize market, fast-changing technology and shortening product life cycle, businesses are becoming extremely competitive, and a cooperative buyer–supplier relationship is essential for a manufacturer, especially in technology-related industry, to survive and to acquire reasonable profit. Even though the research on various types of collaborations between firms is abundant, the research ...

The implementation of building retrofitting processes targeting higher energy efficiency is greatly influenced by the investor’s expectations regarding return on investment. baseline this work assumption that it possible to improve predictability post-retrofit scenario, both in and financial terms, using data gathered how a being used its occupants. proposed approach relies simulation estimate ...

Multimodal transport is a critical component in developing the international trade economy, and logistics service providers are multimodal transport. However, recent COVID-19 pandemic has seriously affected system, especially light of ongoing rise transportation costs which increased firm operating costs. Furthermore, severely influenced economic sector, resulting decreased growth. This researc...

In manufacturing sectors, firms are paying an increasing attention to sustainability concept with regard to their end-of-life products in order to respect environmental norms and satisfy the consumer sensitivity. This practise allows creating value by reintroducing dismantling and recovering parts and/or materials of end-of-life products into manufacturing process, or into maintenance process. ...

abstract minimizing service cost and adverse effects on environment and society are important in waste management. due to this, landfill and transfer station location become important. this article as a practical research uses analytical hierarchy process in multi criteria decision making considering environmental and social criteria in levels of benefit, opportunity, cost and risk (bocr) for p...

سابقه و هدف: ورود گونه­­ های ماهی مهاجم دراکوسیستم ­های آبی، سبب بروز انواع اثرات منفی اکولوژیکی اقتصادی-اجتماعی می ­­شود. اولین گام در تجزیه تحلیل مخاطرات ناشی از گونه­ غیر­بومی، شناسایی خطر است بر این اساس ابزارهای متعددی برای ارزیابی خطرات تهاجمی غیربومی به منظور پشتیبانی تصمیم گیرندگان گونه ­­ها ایجاد شده است. هدف پژوهش قدرت تیلاپیای شکم قرمز (Coptodon zillii) حوضه آبریز تالاب شادگان (حوضه‌...