Distributed knowledge representation (KR) encodes both entities and relations in a lowdimensional semantic space, which has significantly promoted the performance of relation extraction and knowledge reasoning. In many knowledge graphs (KG), some relations indicate attributes of entities (attributes) and others indicate relations between entities (relations). Existing KR models regard all relat...

Previous modeling studies have suggested that the rapid component of the delayed rectifier (I(Kr)) may contribute importantly to action potential dynamics during tachycardia. To test this idea experimentally, I(Kr) was measured as the E-4031-sensitive current in isolated canine endocardial myocytes at 37 degrees C using the perforated patch-clamp technique. Command potentials were trains of act...

Molecular dynamics simulations of water with both multi-Kr and single Kr atomic solutes are carried out to implement quasi-chemical theory evaluation of the hydration free energy of Kr(aq). This approach obtains free energy differences reflecting Kr-Kr interactions at higher concentrations. Those differences are negative changes in hydration free energies with increasing concentrations at const...

Krüppel (Kr) encodes a zinc finger-type transcription factor expressed in spatially and temporally restricted patterns during Drosophila embryogenesis. Molecular targets and the mechanism of Kr action have been studied extensively during the early segmentation process, but only little is known about Kr requirement during later development. We report the identification of a target gene of Kr, te...

During embryonic development, restricted expression of the regulatory genes Krox20 and kreisler are involved in segmentation and antero-posterior patterning of the hindbrain neural tube. The analysis of transgenic mice in which specific rhombomeres (r) are eliminated points to an important role of segmentation in the generation of neuronal networks controlling vital rhythmic behaviours such as ...

A lacunary sequence is an increasing integer sequence θ = (kr) such that k0 =0, kr−kr−1 →∞ as r →∞. A sequence x is called Sθ(∆)− convergent to L provided that for each ε > 0, limr(kr − kr−1) {the number of kr−1 < k ≤ kr : |∆xk−L| ≥ ε} = 0, where ∆xk = ∆xk− ∆xk+1. The purpose of this paper is to introduce the concept of ∆ − lacunary statistical convergence and ∆-lacunary strongly convergence an...

The single atom counting rate of a rare isotope and the loading rate of another stable isotope with an abundance over 10 orders of magnitude larger are measured in one atom trap. The linear correlation between the measured counting/loading rates is examined to determine the (84)Kr/(82)Kr and (85)Kr/(83)Kr ratios of a Kr gas sample. Experiments show that the relative uncertainty is reduced to 1....

Blocking of poly(ADP-ribose) polymerase (PARP)-1 has been expected to protect the heart from ischemia-reperfusion injury. We have recently identified a novel and orally active PARP-1 inhibitor, KR-33889 [2-[methoxycarbonyl(4-methoxyphenyl)-methylsulfanyl]-1H-benzimidazole-4-carboxylic acid amide], and its major metabolite, KR-34285 [2-[carboxy(4-methoxyphenyl)methylsulfanyl]-1H-benzimidazole-4-...

In order to investigate the gas separation ability of a column packed with nanozeolitic material, nano NaY zeolite was synthesized and granulated. These uniform granules packed in a chromatographic column were utilized for separation of Xe and Kr under various operating conditions. With regards to the response peaks obtained from trace injections of Xe and Kr into the column, the first and seco...

Although inactivation of the rapidly activating delayed rectifier current (I(Kr)) limits outward current on depolarization, the role of I(Kr) (and recovery from inactivation) during repolarization is uncertain. To characterize I(Kr) during ventricular repolarization (and compare with the inward rectifier current, I(K1)), voltage-clamp waveforms simulating the action potential were applied to ca...