Selected reaction monitoring (SRM), also called multiple reaction monitoring, has become an invaluable tool for targeted quantitative proteomic analyses, but its application can be compromised by nonoptimal selection of transitions. In particular, complex backgrounds may cause ambiguities in SRM measurement results because peptides with interfering transitions similar to those of the target pep...

BACKGROUND MET gene amplification and Met protein overexpression may be associated with a poor prognosis. The MET/Met status is typically determined with fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC), respectively. Targeted proteomics uses mass spectrometry-based selected reaction monitoring (SRM) to accurately quantitate Met expression. FISH, IHC, and SRM analyses we...

Selected reaction monitoring (SRM), also called multiple reaction monitoring, has become an invaluable tool for targeted quantitative proteomic analyses, but its application can be compromised by nonoptimal selection of transitions. In particular, complex backgrounds may cause ambiguities in SRM measurement results because peptides with interfering transitions similar to those of the target pep...

The incompressibility constraint makes Navier-Stokes equations difficult. A reformulation to a better posed problem is needed before solving it numerically. The sequential regularization method (SRM) is a reformulation which combines the penalty method with a stabilization method in the context of constrained dynamical systems and has the benefit of both methods. In the paper, we study the exis...

Ibis paper investigates the application of fuzzy algorithm for the speed control of switched reluctance motor (SRM) drives. For the purpose of performance simulation of closed loop SRM drive, its components are modelled in a systematic manner. Hysteresis current controlled midpoint converter is employed to feed four phase 8/6 SRM. Non-linearity caused by magnetic saturation in the motor is also...

Systematic Review methodology (SRm) is an increasingly popular choice for literature reviews in the Social Sciences. Although, compared to traditional narrative reviews SRm appears timeconsuming and laborious, transparency and replicability of the methodology is argued to facilitate greater clarity of review. Nevertheless, researchers in Industrial, Work and Organizational (IWO) Psychology have...

Due to the highly nonlinearity of the flux-linkage characteristics of Switched Reluctance Motor drives (SRM), accurately modelling is cumbersome. In this paper, the offlinetrained and the online-trained Radial Basis function (RBF) neural network model are proposed for estimating the SRM flux-linkage under running conditions. To investigate the performance of the modelling schemes, the simulatio...

This paper proposes a semi-parametric software reliability model (SRM) based on a mixed gamma distribution, so-called the mixed gamma SRM. In addition, we develop the parameter estimation method for the mixed gamma SRM. Concretely, the estimation method is based on the Bayesian estimation and the parameter estimation algorithm is described by MCMC (Markov chain Monte Carlo) method with grouped ...

Purpose – The purpose of this work is to applicate a sliding mode observer for sensorless control of switched reluctance motor (SRM) drive Design/methodology/approach – This paper presents an evaluation of the sliding-mode observer to estimate the SRM speed and rotor position. Non-linear model of a SRM is used and a computer simulation is developed based on data from an experimental motor syste...