A graph G with n vertices and maximum degree 1G cannot be given weak sense of direction using less than 1G colours. It is known that n colours are always sufficient, and it was conjectured that just 1G + 1 are really needed, that is, one more colour is sufficient. Nonetheless, it has just been shown [2] that for sufficiently large n there are graphs requiring ω(n/ log n) more colours than 1G . ...

The genetic background of rheumatoid arthritis (RA) is only partly understood, and several genes seem to be involved. The matrix metalloproteinases MMP1 (interstitial collagenase) and MMP3 (stromelysin 1) are thought to be important in destructive joint changes seen in RA. In the present study, functional relevant promoter polymorphisms of MMP1 and MMP3 were genotyped in 308 patients and in 110...

Voltage-gated Ca(2+) channels (Ca(V)) are ubiquitously expressed in various cell types and play vital roles in regulation of cellular functions including proliferation. However, the molecular identities and function of Ca(V) remained unexplored in preadipocytes. Therefore, whole cell voltage-clamp technique, conventional/quantitative real-time RT-PCR, Western blot, small interfering RNA (siRNA)...

T-type Ca(2+) currents have been proposed to be involved in the genesis of spike-and-wave discharges, a sign of absence seizures, but direct evidence in vivo to support this hypothesis has been lacking. To address this question, we generated a null mutation of the alpha(1G) subunit of T-type Ca(2+) channels. The thalamocortical relay neurons of the alpha(1G)-deficient mice lacked the burst mode...

We consider the problem where is an unknown permutation on f0; 1; : : : ; 2n 1g, y0 2 f0; 1; : : : ; 2n 1g, and the goal is to determine the minimum r > 0 such that r(y0) = y0. Information about is available only via queries that yield x(y) from any x 2 f0; 1; : : : ; 2m 1g and y 2 f0; 1; : : : ; 2n 1g (where m is polynomial in n). The resource under consideration is the number of these queries...

The study aim to develop simple, sensitive, rapid, accurate and precise spectrophotometric method for estimation on albendazole and ivermectin in tablet dosage forms. Pure drug sample of albendazole and ivermectin were dissolved in a mixture of methanol and 1 N HCl (70:30). Two wavelengths selected for formation and solving the simultaneous equations were 248.8 nm for albendazole and 314.4 nm f...