Chronic ulcerative stomatitis (CUS) is a mucocutaneous disorder which is characterised by persistent oral mucosal ulceration. The clinical appearance is often reminiscent of oral lichen planus (OLP) leading to erroneous diagnoses. The immune mediated inhibition of the CUS protein (CUSP) is implicated in the pathogenesis of CUS. CUSP acts as an anti-apoptotic protein and when its action is preve...

BACKGROUND Pancreatic cancer treatment is limited and effective drugs are needed. We investigated cucurmosin (CUS)-induced apoptosis in cystic fibrosis pancreatic adenocarcinoma cells (CFPAC-1) and a possible mechanism of action to evaluate the clinical application potential of this new Type I ribosome-inactivating protein. METHODS We analyzed the growth inhibition and apoptosis of CFPAC-1 ce...

Visible light photocatalytic H(2) production through water splitting is of great importance for its potential application in converting solar energy into chemical energy. In this study, a novel visible-light-driven photocatalyst was designed based on photoinduced interfacial charge transfer (IFCT) through surface modification of ZnS porous nanosheets by CuS. CuS/ZnS porous nanosheet photocataly...

New CuS nanocrystals with a 3D hierarchical branched structure are successfully synthesized through in situ consecutive reaction method with copper foam as template. The formation mechanism of the 3D hierarchical branched structure obtained from the secondary reaction is investigated by adjusting the reaction time. The morphology of CuS nanosheet arrays with the 3D hierarchical branched structu...

Copper sulfide nanotubes and nanoparticles have been successfully synthesized by a hydrothermal process at 160 °C for 10 h, employing copper chloride (CuCl2·2H2O) and thioacetamide as starting materials, polyethylene glycol 400 as surfactant. The products are characterized by X-ray power diffraction, scanning electron microscopy, UV–vis spectroscopy and fluorescence spectroscopy, respectively. ...

During spreading and migration, the leading edges of cells undergo periodic protrusion-retraction cycles. The functional purpose of these cycles is unclear. Here, using submicrometer polydimethylsiloxane pillars as substrates for cell spreading, we show that periodic edge retractions coincide with peak forces produced by local contractile units (CUs) that assemble and disassemble along the cell...

(b) bilateral CuS after a technically inadequate CtPa. A repeat CTPA should be performed only if a review of prior study suggests a technical cause that can be remedied or improved. A positive CUS may preclude the need for further tests that involve radiation. Consider repeating the CUS twice, on days 3 and 7. While serial ultrasound has not been directly studied in suspected PE, this strategy ...

A simple, template-free and mild solution chemistry route was employed to synthesize diverse copper sulfide (CuS) nanostructured assemblies at 70 °C by varying the solvent (water or ethylene glycol, or their ratios (3:1, 1:1 and 1:3)). The CuS structures in the shape of spheres and nanotubes were found to be assemblies of either nanoplates or nanoparticles. The nanotube formation was elaboratel...

Contrast-enhanced ultrasound (CEUS) has been used for diagnosing acute pancreatitis (AP), particularly severe acute pancreatitis (SAP). However, the diagnostic difference between CEUS and conventional ultrasonography (CUS) for AP and SAP has not been reported. The aim of the present study was to investigate the diagnostic accuracy of CUS and CEUS for AP. A total of 196 patients clinically diagn...

Carboxylic acid functionalized graphene oxide-copper (II) sulfide nanoparticle composite (GO-COOH-CuS) was prepared from carboxylated graphene oxide and copper precursor in dimethyl sulfoxide (DMSO) by a facile synthesis process at room temperature. The high-effective combination, the interaction between GO-COOH sheets and CuS nanoparticles, and the enhanced visible light absorption were confir...