OBJECTIVE To explore mediators of gender and educational differences in sugarsweetened soft drinks consumption (SDC) and whether gender and level of future education moderate the associations of accessibility, modelling, attitudes and preferences with SDC. DESIGN A cross-sectional school-based survey within the Fruits and Vegetables Makes the Marks (FVMM) project from 2005. SETTING The ques...

AIMS To determine the effects of digoxin on all-cause mortality and heart failure (HF) hospitalizations, regardless of ejection fraction, accounting for serum digoxin concentration (SDC). METHODS AND RESULTS This comprehensive post-hoc analysis of the randomized controlled Digitalis Investigation Group trial (n=7788) focuses on 5548 patients: 1687 with SDC, drawn randomly at 1 month, and 3861...

Syndecans are receptors for soluble ligands, including heparin-binding growth factors, and matrix proteins. However, intracellular targets of syndecan-1 (Sdc-1)-mediated signaling are not fully understood. A yeast two-hybrid protein interaction screening of a mouse embryo library identified the ubiquitin and SUMO-1 E3 ligase, Topors, as a novel ligand of the Sdc-1 cytoplasmic domain (S1CD), a f...

BACKGROUND Reported values of the minimal important change (MIC) and the smallest detectable change (SDC) for the neck disability index (NDI) differ strongly, raising questions about the generalizability of these parameters. The SDC and the MIC are possibly influenced by the study design or by the study population. We studied the influence of the type of anchor, the definition of improvement an...

Memory consolidation is facilitated by sleep. Specifying the functional domain of sleep-dependent consolidation (SDC) is important for identifying the neural mechanisms underlying this phenomenon. Previous work indicates that SDC may be limited to conditions in which learning is explicit. In the present study, we tested the hypothesis that SDC may also occur with implicit learning when learning...

During the summer of 1996 a series of ̄ight tests demonstrated a new indirect-adaptive approach to recon®gurable ̄ight control known as the self-designing controller (SDC). The SDC achieves improved, appropriately decoupled responses during arbitrary effector or airframe impairment scenarios, and successful SDC ̄ight tests culminated with smooth landing of the VISTA/F-16 in crosswind conditions...

PURPOSE To determine the prevalence of spheroidal degeneration of cornea (SDC) and its association with other eye diseases in the tribes of South-West Rajasthan. METHODS A total of 5012 patients were examined on slit lamp for the diagnosis of SDC. Diagnosis of SDC was made based on presence of amber granules in the superficial stroma of peripheral interpalpebral cornea with increasing opacifi...

To perform statistical disclosure control (SDC) on tabular data is a challenging task because we need to ensure that every suppressed cell of a table has a suffi cient width of a confi dentiality interval under the presence of linear relations among cell variables. However, we fi nd that the existing SDC tool (i.e., τ-ARGUS) does not effectively support an output checking process of the on-site...

Salivary duct carcinoma (SDC) is an aggressive malignant tumor with a high mortality, which resembles high-grade breast ductal carcinoma in morphology. The parotid gland is the most common location. Its molecular genetic characteristics remain largely unknown. We have previously reported high incidence of PIK3CA somatic mutations in head and neck squamous cell carcinoma, particularly in pharyng...

Makkonen and his colleagues published an article in the Journal of Virology entitled “6-Oand N-Sulfated Syndecan-1 Promotes Baculovirus Binding and Entry into Mammalian Cells” (1). Some parts of the data and conclusions seem misleading and not fully justified. Heparan sulfate (HS) alone can bind baculovirus to cells during entry and transduction. Syndecan-1 (SDC-1) contains a protein core and H...