The lac operon of Escherichia coli is the paradigm for gene regulation. Its key component is the lac repressor, a product of the lacI gene. The three-dimensional structures of the intact lac repressor, the lac repressor bound to the gratuitous inducer isopropyl-beta-D-1-thiogalactoside (IPTG) and the lac repressor complexed with a 21-base pair symmetric operator DNA have been determined. These ...

An F-lac plasmid from Escherichia coli was transferred to virulent Yersinia pestis, resulting in the repression of virulence. The Y. pestis F-lac clones retained all of the known virulence traits but were avirulent and calcium independent. Every lac segregant derived from the F-lac clones was fully virulent and calcium dependent.

We present a study of the intraday variability behaviour of two samples of X-ray selected BL Lac objects, the EMSS and EXOSAT samples consisting of 22 and 11 sources, respectively. In both samples we were able to detect intraday variability in less than 40% of the sources only. The duty cycle (the fraction of time, when a BL Lac object is variable) in X-ray selected BL Lac objects is 0.4 or les...

We present a study of the intraday variability behaviour of two samples of x-ray selected BL Lac objects, the EMSS and EXOSAT samples consisting of 22 and 11 sources, respectively. In both samples we were able to detect intraday variability in less than 40% of the sources only. The duty cycle (the fraction of time, when a BL Lac object is variable) in x-ray selected BL Lac objects is 0.4 or les...

Introduction. Lung adenocarcinoma (LAC) is the most frequent type of lung cancer and has a high metastatic rate at an early stage. This study is aimed at identifying LAC-associated genes. Materials and Methods. GSE62950 downloaded from Gene Expression Omnibus included a DNA methylation dataset and an mRNA expression profiles dataset, both of which included 28 LAC tissue samples and 28 adjacent ...

In a system described by Cairns and Foster, starvation of a particular leaky lac mutant (lacIZ33) in the presence of lactose appears to direct mutation in non-growing cells to sites that allow growth (adaptive mutation). This behaviour requires that the lac operon be located on an F' plasmid. This position effect was investigated by placing the mutant lac operon at many sites in the genome of S...

Bisphenols are important industrial materials for example the production of plastics, but also well known their adverse health effects, in particular bisphenol A (BPA) is an endocrine disruptor. The widespread use plastics has raised concerns. Therefore, removal bisphenols from wastewater sparked interest scientific community. This work introduces a novel hybrid technique micro-nano bubbles ass...

Recently, many studies showed that long noncoding RNAs (lncRNAs) are involved in tumor progression. It is reported that lncRNA-LET is downregulated and has antitumor effect on several types of cancer. This study focuses on the role of lncRNA-LET on lung adenocarcinoma (LAC) progression. RT-PCR results indicated that frequent downregulation of lncRNA-LET in LAC tissues was related to clinicopath...

This is the first time seroprevalence of antibody to these nine infectious diseases have been available for LAC. Differences in the race and ethnicity distribution of the United States and LAC were observed. Because disease prevalence varies by race and ethnicity, in some instances these demographic differences affected the population differences seen between the United States and LAC in the se...

The mass of light absorbing carbon (LAC) in individual, internally mixed aerosol particles was measured with the Single Particle Soot Photometer (SP2) in April of 2003 and 2005 and evaluated with respect to concentrations of carbon monoxide (CO), particle bound polycyclic aromatic hydrocarbons (PPAH) and condensation nuclei (CN). The LAC and CO have matching diurnal trends that are linked to tr...