Cyclophosphamide (CP) is extensively used as an antineoplastic agent for the treatment of various cancers, as well as an immunosuppressive agent. However, despite its wide spectrum of clinical uses, CP is known to cause several adverse effects including reproductive toxicity. Crataegus monogyna is one of the oldest pharmaceutical plants that have been shown to be cytoprotective by scavenging fr...

Crataegus monogyna Jacq. is naturalized in North America, where it has hybridized with native diploid hawthorns at least twice. We provide names for the two nothospecies (as well as for the corresponding nothosections and nothoseries), referring to existing documentation in the literature for nothosp. nov. Crataegus ×ninae-celottiae K.I. Chr. & T.A. Dickinson (C. monogyna × C. punctata Jacq.). ...

H awthorn, a Crataegus species, is part of a genus of spiny shrubs and trees native to temperate regions in the Northern Hemisphere in Europe, Asia, and North America. Depending on the taxonomic interpretation, between 200 and 1,000 species of Crataegus have been recognized. Hawthorn is the oldest known medicinal plant in European medicine; its actions on the heart were first described by Diosc...

A phytochemical study of two plant species, Viscum cruciatum Sieber and Crataegus monogyna Jacq., was completed to investigate the influence of the parasite Viscum cruciatum on the host Crataegus monogyna. The study was carried out with two samples and consisted of hexane extracts of the Viscum cruciatum parasitizing on Crataegus monogyna and C monogyna. In these samples ursolic acid, beta-sito...

Investigations on procyanidin profile on Bulgarian Crataegus oxycantha fruits extract has been carried out by different analytical approaches based on chromatographic methods. We retained of interest to test the validity of direct infusion of Crataegus extract in ESI conditions to achieve an immediate fingerprinting of the procyanidins therein contained. The results are compared with those obta...