Acoustics 08 Paris 5101 To gain a better understanding of the long-observed effects of vocalic context, the articulation of fricatives was investigated using Magnetic Resonance Imaging. Five speakers of American English were imaged while producing eight fricatives in the contexts /i-a-u-@/. Sagittal, axial and oblique-coronal volumes were acquired for each vowel-fricative combination. Acoustic ...

Natural killer (NK) cells kill normal and transformed hematopoietic cells that lack expression of major histocompatibility complex (MHC) class I antigens. Lysis of HLA-negative Epstein Barr virus-transformed B lymphoblastoid call lines (B-LCL) by human NK cell clones can be inhibited by transfection of the target cells with certain HLA-A, -I3, or -C alleles. NK cell clones established from an i...

Analogs of 1,25-dihydroxyergocalciferol, modified in the side-chain and in the A-ring, were tested for their antiproliferative activity against a series of human cancer cell lines in vitro and in vivo toxicity. The proliferation inhibition caused by the analogs was higher than that of the parent compounds, while the toxicity, measured as the serum calcium level, was lower. All analogs were able...

Over the past years, Service-Oriented Architectures have become a paradigm in enterprises for enabling more efficient and flexible business processes and addressing some of the technological challenges posed by the service-based economy. Using loosely coupled services, they allow for discovery, composition and orchestration capabilities that are needed by end-users, business processes or other ...

Ryanodine receptors (RyRs) play a critical role in regulating the release of intracellular calcium, which enables them to be effectively targeted by the two novel classes of insecticides, phthalic acid diamides and anthranilic diamides. However, less information is available about this target site in insects, although the sequence and structure information of target molecules are essential for ...

OBJECTIVE To review the progress in the field of MHC-related genetic susceptibility to Behçet's disease (BD). METHOD Systematic review of the English literature between 1 January 1980 and 31 January 2010 using Medline. Case-control, population-based, observational cohort studies investigating the association between BD and HLA-B*51 subtypes, classical and non-classical HLA alleles and other H...

The alkylating potential of beta-propiolactone (BPL), beta-butyrolactone (BBL), gamma-butyrolactone, and delta-valerolactone, which can be formed by the in vivo nitrosation of primary amino acids, was investigated kinetically. The nucleophile NBP, 4-(p-nitrobenzyl)pyridine, a trap for alkylating agents, was used as an alkylation substrate. The alkylation reactions were performed under mimicked ...

This document specifies the IP Flow Information Export (IPFIX) protocol, which serves as a means for transmitting Traffic Flow information over the network. In order to transmit Traffic Flow information from an Exporting Process to a Collecting Process, a common representation of flow data and a standard means of communicating them are required. This document describes how the IPFIX Data and Te...

We show that endothelial cell (EC)– generated vascular guidance tunnels (ie, matrix spaces created during tube formation) serve as conduits for the recruitment and motility of pericytes along EC ablumenal surfaces to facilitate vessel maturation events, including vascular basement membrane matrix assembly and restriction of EC tube diameter. During quail development, pericyte recruitment along ...