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and Applied Analysis 3 Table 1: Solitary wave Amp. 0.3 and the errors in L2 and L∞ norms for u, Q 1 , Q 2 , and Q 3 at t = 20, h = 0.125, Δt = 0.1, and −40 ≤ x ≤ 60. Method Time Q 1 Q 2 Q 3 L 2 for u L∞ for u Our method 0 3.9797 0.8104 2.5787 0 0 4 3.9797 0.8104 2.5786 3.6304e − 004 5.2892e − 005 8 3.9797 0.8104 2.5786 7.2873e − 004 5.8664e − 005 12 3.9797 0.8104 2.5787 1.0817e − 003 6.3283e − ...
GluN2A is the most abundant of the GluN2 NMDA receptor subunits in the mammalian CNS. Physiological and genetic evidence implicate GluN2A-containing receptors in susceptibility to autism, schizophrenia, childhood epilepsy and neurodevelopmental disorders such as Rett Syndrome. However, GluN2A-selective pharmacological probes to explore the therapeutic potential of targeting these receptors have...
The incidence and factors associated with inappropriate use of antifungal medications were studied in a Thai tertiary care center. The incidence of inappropriate antifungal use was 74% (in 42 of 57 patients). Isolation of Candida species from urine (P = .004) was a risk factor, whereas receipt of an infectious diseases consultation (P = .004) was protective.
PURPOSE Endosialin (TEM-1, CD248) is a protein expressed on the surface of activated mesenchymal cells, including certain subsets of tumors. Preclinical models suppressing endosialin function have shown antitumor activity. A humanized monoclonal antibody, MORAb-004, was engineered to target endosialin and is the first agent in clinical development for this mesenchymal cell target. EXPERIMENTA...
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