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OBJECTIVES HLA-DRB1*03 is strongly associated with anti-Jo-1-positive idiopathic inflammatory myopathies (IIM) and there is now increasing evidence that Jo-1 antigen is preferentially expressed in lung tissue. This study examined whether smoking was associated with the development of anti-Jo-1 antibodies in HLA-DRB1*03-positive IIM. METHODS IIM cases were selected with concurrent information ...
published by admin on Fri, 03/14/2014 9:08am Title Primary care and public health partnerships for implementing pre-exposure prophylaxis. Publication Type Journal Article Year of Publication 2013 Authors Norton, WE, R Larson, S, Dearing, JW Journal Am J Prev Med Volume 44 Issue 1 Suppl 2 Pagination S77-9 Date Published 2013 Jan ISSN 1873-2607
PURPOSE To determine risk factors of umbilical cord blood transplantation (UCBT) for patients with lymphoid malignancies. PATIENTS AND METHODS We evaluated 104 adult patients (median age, 41 years) who underwent unrelated donor UCBT for lymphoid malignancies. UCB grafts were two-antigen human leukocyte antigen-mismatched in 68%, and were composed of one (n = 78) or two (n = 26) units. Diagnos...
published by admin on Fri, 03/14/2014 8:53am Title Digitoxin metabolism by rat liver microsomes. Publication Type Journal Article Year of Publication 1975 Authors Schmoldt, A, Benthe, HF, Haberland, G Journal Biochem Pharmacol Volume 24 Issue 17 Pagination 1639-41 Date Published 1975 Sep 1 ISSN 0006-2952
Title: In-screw polymethylmethacrylate-augmented sacroiliac screw for the treatment of fragility fractures of the pelvis: a prospective, observational study with 1-year follow-up Authors: Andreas Höch ([email protected]) Philipp Pieroh ([email protected]) Ralf Henkelmann ([email protected]) Christoph Josten ([email protected]...
The authors dealt with some hazardous elements, i.e. As, Cd, Co, Cr, Cu, Ni, Pb and Zn, contained in sands of the sandboxes localized in playgrounds of seven spas in southern Poland (CEE). The following determinations were made: the total contents of metals, the most mobile metals (water-leachable fraction) and the metals available to plants and organisms (CaCl2- and EDTA-extractable fractions)...
We recently identified the protein phosphatase-1 - targeting compound, 1E7-03 which inhibited HIV-1 in vitro. Here, we investigated the effect of 1E7-03 on HIV-1 infection in vivo by analyzing its metabolic stability and antiviral activity of 1E7-03 and its metabolites in HIV-1 infected NSG-humanized mice. 1E7-03 was degraded in serum and formed two major degradation products, DP1 and DP3, whic...
Temporary Shocks and Offshoring: The Role of External Economies and Firm Heterogeneity We construct a model of offshoring with externalities and firm heterogeneity. Due to the presence of externalities, temporary shocks like the Y2K problem can have permanent effects, i.e., they can permanently raise the extent of offshoring in an industry. Also, the initial advantage of a country as a potentia...
BACKGROUND Morbidity and mortality are higher among human immunodeficiency virus (HIV) exposed but uninfected (HEU) infants than unexposed infants, particularly if the mother had a low CD4 count. We investigated the possible association between maternal immune depression during pregnancy and the risk of infection in HEU infants in the national French Perinatal Cohort (EPF). METHODS All neonat...
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