Abstract Introduction Insomnia is one of the most prevalent health concerns in general population. Cognitive behavioural therapy (CBT) and pharmacological interventions are recommended for treatment insomnia. However, CBT can be expensive difficult to access, while use pharmacotherapy limited by reports adverse events. Due these limitations, there a strong need alternative measures manage Preli...

Introduction Controversy surrounds reconstruction of the anterior cruciate ligament (ACL) with regards to graft choice and fixation. Most surgeons performing ACL reconstruction use an intra-articular autogenous graft from either the patellar tendon or hamstrings. It has been suggested that hamstring tendon grafts are weaker than patellar tendon grafts, although there is conflicting data where m...

The systemic effects of physical activity are mediated by the release IL-6 and other myokines from contracting muscle. Although muscle has been extensively studied, information on cellular mechanisms is fragmentary scarce, especially regarding role Ca2+ signals. aim this study was to characterize main components signals in human skeletal cells during secretion stimulated mobilizing agonist ATP....