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074 0 -74 5 9 /12 / $ 31. 0 0 © 2 012 I E E E Steve McConnell deSCribed technical debt as including both intentional and unintentional violations of good architectural and coding practice1—an expansion of Ward Cunningham’s original focus on intentional decisions to release suboptimal code to achieve objectives such as faster delivery.2 By choosing debt as a metaphor, Cunningham engaged a set of...

Tao Peng 1, Peng Yang 1 , Hanbing Dan 1,* , Hui Wang 1, Hua Han 1, Jian Yang 1, Hao Wang 1, Hui Dong 1 and Patrick Wheeler 2 1 School of Information Science and Engineering, Central South University, Changsha 410083, China; [email protected] (T.P.); [email protected] (P.Y.); [email protected] (H.W.); [email protected] (H.H.); [email protected] (J.Y.); [email protected] (...

The effective equations of motion for low-frequency mean gauge fields in the Abelian Higgs model are investigated in the presence of a scalar condensate, near the high temperature equilibrium. We determine the current induced by an inhomogeneous background gauge field in the linear response approximation up to O(e), assuming adiabatic variation of the scalar fields. The physical degrees of free...

The stereoselective synthesis of cathepsin inhibitors from indoline type epoxyamides is described. The use of this type of epoxyamides permitted the preparation of E-64 and CA-074 related compounds depending on the order in which the key steps, the oxidation of indoline amides to indole amides and oxidative acetal cleavage were undertaken. By taking advantage of the facile substitution of the i...