A one-pot three-component [2+3] cycloaddition for the synthesis of 1-alkyl 1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione and 2-alkyl 2H-naphtho[2,3-d][1,2,3]triazole-4,9-dione has been developed. By taking the advantage of difference in basicity, both products can be obtained in good purity. The unique heterocyclic scaffolds of these two products could exert interesting chemical and biological pro...

The title compound, C21H12Br2F13NO·2CH3OH, was obtained by condensation of 4-methyl-1-(1H,1H,2H,2H-perfluoro-oct-yl)pyridinium iodide and 3,5-di-bromo-4-hy-droxy-benzaldehyde, followed by deprotonation. It crystallizes as a methanol disolvate and exhibits short O-H⋯O hydrogen bonds and a disordered perfluoro-alkyl chain [occupancy ratio 0.538 (7):0.462 (7)]. Significant π-π stacking inter-actio...

The reaction of dibenzoylacetylene with 4-alkylaminocoumarins in THF/H2O (50:50) lead to 4-(alkylamino)-3-(1,4-dioxo-1,4-diphenylbut-2-en-2-yl)-2H-chromen-2-one derivatives in good yields. When the reaction carried-out in DMSO the cyclized products 2-hydroxy-1-alkyl-3-(2-oxo-2-phenylethylidene)-2-phenyl-2,3-dihydrochromeno [4,3-b] pyrrol-4(1H)-ones were formed in good yields.

Abstract- Some new 3-(alkylsulfanyl)- 7-chloro-1-phenyl-1H-pyridazino [4,3-e][1,3,4]thiadiazine were synthesized  by treatment of the alkyl-2-phenylhydrazinecarbodithioates with 4-bromo-3,6-dichloropyridazine in alkaline acetonitril. Orientation of the reaction has been determined by X-Ray crystallography technique. The chlorine atom on the number 7 position of these products was repla...

New 1,5-tetra alkyl methyl- phenyl-1H-pyrimido[4,5-e][1,3,4]thiadiazine-3,7-diamine  were synthesized via the cyclo condensation of 2-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-2-methylhydrazine with phenylthioisothiocyanate  and further replacement of chlorine atom on the seven number position of pyrimido[4, 5- e][1, 3, 4]thiadiazin by appropriate secondary amines  in simple a...

The synthesis of 3-alkyl(aryl)-4-(3-ethoxy-4-hydroxybenzylidenamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones 3 from the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones 2 with 3-ethoxy-4-hydroxybenzaldehyde is described. The acetylation and methylation reactions of the compounds 3 giving compounds of type 4 and 5, respectively, were investigated. The newly synthesized compound...