The 1H chemical shifts of benzaldehyde, 2-chloro-, 2-hydroxyand 2-methoxybenzaldehyde, acetophenone, 2-methoxyand 2-hydroxyacetophenone, indanone, anthraquinone, fluorenone, anthrone,a-tetralone, 2,4,6trimethylacetophenone, 9-acetylanthracene, 9-anthranaldehyde and benzosuberone were obtained and completely assigned in CDCl3 and DMSO solution. In anthrone a keto–enol tautomerism (anthrone–9hydr...

Nine compounds, 3-hydroxy-4,5-dimethoxyphenyl-beta-D-glucopyranoside (1), beta-D-fructfuranosyl-alpha-D-(6-vanilloyl)-glucopyranoside (2), beta-D-fructfuranosyl-alpha-D-(6-syringyl)-glucopyranoside (3), 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxy-1-(E)-propenyl)-2-methoxyphenoxy]propyl-beta-D-glucopyranoside (4), 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxy-1-(E)-propenyl...

Glaberianthrone (1), a new bianthrone was isolated from the hexane extract of the stem bark of Psorospermum glaberrimum together with thirteen known compounds: 3-geranyloxyemodin anthrone (2), friedelan-3-one (3), 3-prenyloxyemodin anthrone (4), 3-geranyloxyemodin (5), 3-prenyloxyemodin (6), friedelan-3-ol (7), acetylvismione D (8), betulinic acid (9), 2-geranylemodin (10), bianthrone A2b (11),...

In the course of synthesizing 3-demethyltylophorine (1) by Lewis acid catalyzed intramolecular Friedel-Crafts reaction starting from N-(3-hydroxy-2,6,7-trimethoxy-phenanthr-9-ylmethyl)-2-chloromethylpyrrolidine, two chlorinated phenanthrene derivatives N-(4,10-dichloro-3-hydroxy-2,6,7-trimethoxyphenanthr-9-ylmethyl)-2-chloromethylpyrrolidine (4) and N-(4-chloro-3-hydroxy-2,6,7-trimethoxyphenant...

Thin-layer chromatography (TLC) was used to analyze lipids of eight spleens of patients with Gaucher’s disease. Four non-Gaucher spleens were also analyzed. Phospholipid concentrations are not increased in Gaucher spleens, while several classes of neutral lipids are moderately increased. Acid hydrolysis followed by hexose determination was applied to total lipids and to separated fractions. Spe...

Hans W. Rauwald and Anette Beil Institut für Pharmazeutische Biologie, Johann Wolfgang Goethe-Universität, Georg-Voigt-Straße 16, D-W-6000 Frankfurt am Main 11, Bundesrepublik Deutschland Z. Naturforsch. 48c, 1 -4 (1993); received December 12, 1992 Aloe, Asphodelaceae, 5-Hydroxyaloin A, Quinones, Chemotaxonomy By a comparative thin layer chromatographic screening of the methanol-soluble leaf ex...

Three 3-hydroxymonoazine- and three N-hydroxydiazine-type heterocycles were tested whether they act as artificial siderophores toward Aureobacterium flavescens JG-9 (ATCC No. 25091). Among them, 1-hydroxy-3,5,6-trimethyl-2(1H)-pyrazinone (3) showed the highest growth-promotion activity comparable to desferrioxamine B (DFB), a natural trihydroxamate siderophore, at 48.5 microM or above, followed...

Episesamin is an isomer of sesamin, resulting from the refining process of non-roasted sesame seed oil. Episesamin has two methylendioxyphenyl groups on exo and endo faces of the bicyclic skeleton. The side methylendioxyphenyl group was metabolized by cytochrome-P450. Seven metabolites of episesamin were found in rat bile after treatment with glucuronidase/arylsulfatase and were identified usin...

An isomeric mixture of linoleic acid hydro peroxides, 13-hydroperoxy-cis9 trans-II-octadecadienoic acid (79%) a~d 9-hydroperoxy-eis-12,trans-IO-octadecadienoic acid (21 %), was decomposed homolytically by Fe(I!) in an ethanolwater solution. In one series of experiments, the hydroperoxides were decomposed by catalytic concentrations of Fe (II). The 10.5 M Fe(III) used to initiate the decompositi...