BACKGROUND Rhabdomyolysis is a clinical and biochemical syndrome, which is observed in some patients with acute chemical and/or pharmaceutical poisonings. We aimed to investigate rhabdomyolysis in patients with acute poisonings due to different chemicals, natural toxins or drug overdose. MATERIALS AND METHODS Following approval of the University medical research committee and obtaining inform...

6-Hydroxymethylacylfulvene (MGI-114) is a semisynthetic analogue of the toxin illudin S, a product of the Omphalotus mushroom. MGI-114 induces cytotoxicity in a variety of solid tumors in vivo, including the refractory HT29 human colon cancer xenograft. In this study, the potential application of MGI-114 in the treatment of colon cancer was further explored by evaluating the activity of MGI-114...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 1. Evolution of the Concept and Definition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102 2. Epidemiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

The purpose of r2 is to protect Alice’s secret bit b. To find b before Alice opens the commitment, Bob would have to find r′ 2 and b ′ such that H(r1r 2b ′) = c. This is akin to the problem of inverting H and is likely to be hard, although the one-way property for H is not strong enough to imply this. On the one hand, if Bob succeeds in finding such r′ 2 and b ′, he has indeed inverted H , but ...

after alzheimer disease, parkinson disease (pd) is considered the most common neurodegenerative disease. its prevalence is the same in all area but it is common in males than females. from every 100 persons who are above 60 years old, one of them has pd. also 5-10% of patients are less than 40 years old. this progressive neuroinflammation disease isn’t fatal. in 60% of cases is with depression....

We performed spoligotyping on 114 strains of the Mycobacterium tuberculosis (Mtb) complex that had been isolated from patients in Minas Gerais Health Units during 2004. A total of 82/114 (72%) clinical isolates were clustered and 32/114 (28%) were unique. Seven shared types containing nine strains were newly created. A total of nine patterns corresponded to unreported orphan strains, as evaluat...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108 The phylogenetic position of Porifera wi...

Four novel oxapenem compounds (i.e., AM-112, AM-113, AM-114, and AM-115) were investigated for their beta-lactamase inhibitory activity against a panel of isolated class A, C, and D enzymes, which included expanded-spectrum beta-lactamase enzymes (ESBLs). The oxapenems were potent beta-lactamase inhibitors. Activity varied within the group, with AM-113 and AM-114 proving to be the most active c...

ion, 18, 67, 81, 82,see also λx.saccept, 114application, 18, 52, 66, 67,115, 126, 131–133,228, 229, 254, 255,257, see also ruleapplicationapproximation, 10, 88, 89,93, 94, 123, 150set-based, 14argument, 87argument context, 76, 76, 77,78 blank symbol, 113, 114 case, 18co-domain, 20, 100, 206combinator, 23fixpoint, 34, 35, 79, 81...