L-arginine can attenuate pulmonary hypertension (PH) by a mechanism that are not fully understood. This study investigated the molecule mechanism of L-arginine attenuating PH. Sprague Dawley rats were treated with monocrotaline (MCT) with or without L-arginine for 3 or 5 wk. Right ventricular systolic pressure (RVSP), right heart hypertrophy, survival rate, pulmonary artery wall thickness, nitr...

Abstract Aim In recent years, numerous minimally invasive techniques have been developed for the repair of midline hernias associated with diastasis recti. The eMILOS technique (Endoscopic mini/less open sublay technique) allows mesh placement in retromuscular space through a small trans-hernial incision without entering abdominal cavity. Material & Methods We present case 45 year-old male ...

Munawwar Ali Abbas 1, Yanqin Bai 1,*, Mohammad Mehdi Rashidi 2,3 and Muhammad Mubashir Bhatti 4 1 Department of Mathematics, Shanghai University, Shanghai 200444, China; [email protected] 2 Shanghai Key Lab of Vehicle Aerodynamics and Vehicle Thermal Management Systems, Tongji University, Shanghai 201804, China; [email protected] 3 ENN-Tongji Clean Energy Institute of Advanced Studies, Sha...

Autoimmune uveitis has been elicited in susceptible rodents by several ocular-specific Ags. In most of these animal models the induced uveitis is acute and monophasic. Because recurrent uveitis poses the highest risk for blinding ocular complications in human disease, a spontaneous relapsing animal model would be most helpful in understanding the disease pathogenesis. In our current study we ha...

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Introduction Mevalonate kinase deficiency (MKD) has a wide spectrum and severity of clinical manifestation. Patients with mutations in MVK gene leading to complete lack of the enzyme, suffer from the most severe form of disease, also known as mevalonic acydosis, whereas defects with preserved, but insufficient enzyme activity present with autoinflammatory syndrome , also known as hiperIgD syndr...