We introduce a new Bayesian approach to the variable selection problem which we term Bayesian Shrinkage Variable Selection (BSVS ). This approach is inspired by the Relevance Vector Machine (RVM ), which uses a Bayesian hierarchical linear setup to do variable selection and model estimation. RVM is typically applied in the context of kernel regression although it is also suitable in the standar...

This issue features articles on the presence of specific “epigenetic” etiology associated with increased risk of developing comorbid dysexecutive and social anxiety symptoms in premutation women carrying the FMR1 gene and on fingolimod treatment andCSF neurofilament light chain levels in relapsing-remitting multiple sclerosis. Another featured article focuses on the factors influencing sweat gl...

2 structure summarizing coalescent events for each portion of the sequence. To allow for population stratification or other constraints on mating, we define a set of rules that can be used to relate each individual sequence (a row in one of the sparse matrices) to its ancestors in the previous generation (one or more rows in the second sparse matrix). Since we simulate all intervening generatio...

World Malaria Day is commemorated each year on April 25, the date in 2000 when leaders of 44 African nations met in Abuja, Nigeria, and committed their countries to reducing the number of malaria-related deaths. Approximately 90% of all malaria deaths occur in Africa (1). During the last 15 years, donors have collectively supported the procurement and distribution of billions of insecticide-tre...