The mechanisms by which prenatal events affect development of adult disease are incompletely characterized. Based on findings in a murine model of maternal transmission of asthma risk, we sought to test the role of the pro-asthmatic cytokines interleukin IL-4 and -13. To assess transplacental passage of functional cytokines, we assayed phosphorylation of STAT-6, a marker of IL-4 and -13 signali...

Of my own situation I wrote: “In one day I typically receive 5-10 pieces of regular junk mail, 15-25 regular letters, 5 pieces of campus mail, 5 reports or documents (not all technical), 5-10 incoming phone calls, 10-20 local electronic messages, and 10-20 external electronic messages. Although many of these messages are discarded or forwarded to others for handling, much of my time is required...

The cytokines interleukin 13 and 4 share a common heterodimeric receptor and are important modulators of peripheral allergic reactions. Produced primarily by T-helper type 2 lymphocytes, they are typically considered as anti-inflammatory cytokines because they can downregulate the synthesis of T-helper type 1 pro-inflammatory cytokines. Their presence and role in the brain is only beginning to ...

Hrvatsko stomatološko društvo HLZ-a, u suradnji s ostalim Društvima HLZ-a organizira Međunarodni kongres stomatologa koji će se održati u Zagrebu od 13. do 15. studenog 2008. godine. Uz pozvane predavače, uvažene i inozemne stručnjake, pozivam Vas sa svojim radovima doprinesete uspjehu Kongresa. Znanstveno-stručni program pratit će i bogata izložba opreme i stomatoloških proizvoda, koji će sudi...

[This corrects the article DOI: 10.5888/pcd13.160262.].

[This retracts the article DOI: 10.5888/pcd13.160044.].

History has had its periods of magnificent excess, when vast amounts of human effort were devoted to cultural projects that transcended the necessities of survival and commerce. Obvious examples begin with the construction of the great pyramids. Much later, Europe's cathedrals were the ultimate commitment of society's surplus energy to expressions of the spirit. The explorations of the remote r...

immune and inflammatory responses mediated by cytokines, play important roles in the pathophysiology of asthma. these responses are associated with overexpression of th2 cytokines such as il-4 and il-13. these two cytokines use common receptors for signaling that lead to identical immunological effects and regulation of the th1/th2 balance. the aim of this study was to determine whether patient...

THE TITLE COMPOUND [SYSTEMATIC NAME: 1(2)-amino-4(2)-(1-naphth-yl)-1,4(1,4)-dibenzenacyclo-hexa-phane], C(26)H(23)N, was synthesized from 4-amino-13-bromo-[2,2]paracyclo-phane and 1-naphthalene-boronic acid in the presence of 1,4-dioxane. It is a new cyclo-phane-derived compound which can be regarded as a prospective ligand for asymmetric synthesis and catalysis. The benzene rings of the paracy...

Data management systems are fast becoming required components in many biology laboratories as the role of Abstract computer-based information grows. Although the need for data management systems is on the rise, their inherent complexities can deter the full and routine use of their computational capabilities. The significant undertaking to implement a capable production system can be reduced in...