نتایج جستجو برای: 131i mibg

تعداد نتایج: 2920  

Journal: :Journal of the Egyptian National Cancer Institute 2006
Hesham Abd El-Aal

BACKGROUND For more than ten years. MIBG has been successfully used in diagnosis and staging of children with neuroblastoma. AIM OF THE STUDY Identify the role of 131I MIBG in the assessment of neuroblastoma and correlate its findings with other non-invasive tests. PATIENTS AND METHODS Twenty eight patients with neuroblastoma attending the Pediatric Oncology Unit, Kasr El-Aini Center of Rad...

2014
STEPHANIE S. WANG RUTH HSIAO MARIKO M. LIMPAR SARAH LOMAHAN TUAN-ANH TRAN NOLAN J. MALONEY NAOHIKO IKEGAKI XAO X. TANG

In the present study, we investigated the anticancer effects of the mitochondrial inhibitors, metaiodobenzylguanidine (MIBG), metformin and phenformin. 131I-MIBG has been used for scintigraphic detection and the targeted radiotherapy of neuroblastoma (NB), a pediatric malignancy. Non-radiolabeled MIBG has been reported to be cytotoxic to NB cells in vitro and in vivo. However, the mechanisms be...

2016

Cite this article: Changmuang W (2016) The Importance of Patient-Specific Dosimetry to Minimize the Risk of Red Marrow Toxicity from 131I-mIBG Therapies. J Radiol Radiat Ther 4(1): 1059. *Corresponding author Changmuang W, Department of Diagnostic and Therapeutic Radiology, Nuclear Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Retchathewi, Bangkok 1040...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006
Samer Ezziddin Timur Logvinski Charlotte Yong-Hing Hojjat Ahmadzadehfar Hans-Peter Fischer Holger Palmedo Jan Bucerius Michael J Reinhardt Hans-Jürgen Biersack

UNLABELLED Radiolabeled octreotide analogs (Oct) and metaiodobenzylguanidine (MIBG) offer 2 different approaches for imaging and targeting metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NET). Despite successful establishment of the revised World Health Organization (WHO) classification, which distinguishes between low- and high-grade malignant GEP-NET, there is a lack of scintigra...

Journal: :Revista espanola de medicina nuclear 2006
B Volkan Salanci E Lay Ergün

I-131 MIBG scintigraphy is routinely used in the diagnosis of neuroendocrine tumours with high specificity. The radiopharmaceutical is taken up via uptake mechanism and actively transported into storage vesicules. The organs with dense sympathetic innervation such as salivary glands, heart, lachrymal glands, spleen and rarely adrenal medulla are normally visualized with I-131 MIBG. Asymetrical ...

Journal: :Onco 2021

Neuroblastoma (NB) represents the most common extracranial tumor of childhood. Prognosis is quite variable, ranging from spontaneous regression to aggressive behavior with wide metastatization, high mortality, and limited therapeutic options. Radiotheranostics combines a radiopharmaceutical pair in unique approach, suitable both for diagnosis therapy. For many years, metaiodobenzylguanidine (MI...

Objective(s): Single-photon emission computed tomography (SPECT) using metaiodobenzylguanidine (MIBG) is an important diagnostic tool for the treatment of refractory pheochromocytoma and paraganglioma (PPGL). Owing to the difficulty of SPECT quantification, the tumour-to-background ratio (TBR) is used to assess disease activity. However, the utility of TBR is limited o...

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