We have investigated the effect of antioxidant-induced apoptosis in human prostate cancer cell lines that is augmented by testosterone (T). In this study, DU-145 (androgen unresponsive), ALVA-101 (partially androgen responsive), and LNCaP (androgen responsive) were grown in tissue culture with RPMI 1640 medium, 5-10% fetal bovine serum (FBS), antibiotics and 5% CO2. Treatment with 2.5-20 microg...

NEO-PI-R و SCL-90-R هنومن يور اه دـمآرد ارجا هب . لـيلحت شور زا نوـمزآ و نوـسريپ یگتسبمه بيرض ،نويسرگر T و هـيزجت یارـب لقتـسم هداد ليلحت دش هدافتسا اه . هتفاي اه : ناور لماع يدنژن (N) صخاش يمامت ،ناوت نيرتلااب اب طوبرم ياه هب SCL-90-R شيپ ار من ينيب و د . عومجم رد ، تيصخش يلصا لماوع شيپ نيرتلااب و نيرتهب ينيب هب ار اه صخاش دروم رد بيترت ياه ينامسج دنتشاد ساره و يربج ساوسو ،ندرك ...

هديكچ فده : و فرصـم عـلو تدـش ناـيم طابترا يسررب فده اب شهوژپ نيا صخاش هـب ناداـتعم يلـصا هورگ هس رد يرگشناكت ياه رد ينوـيفا داوـم ناريا ) كايرت و كارك ،نييوره ( تسا هدش ماجنا . شور : 77 يندومزآ هورگ هس رد داتعم درم : فرصم يقاشـنتسا و يـقيرزت نييورـه هدـننك ) 37 رفن ( فرصم ، ينيخدت كارك هدننك ) 17 رفن ( ينيخدت كايرت و ) 23 رـفن ( هب هـمين هبحاصم كي كمك رايعم اـب قـيبطت و هتفايراتخاـس ر...

UNLABELLED Prostate cancer is a major public health problem in the world. Molecular studies are necessary for the development of prognostic markers in prostate cancer. There is a great interest in mucin studies in treatment development of human malignancies, including prostate cancer. Nevertheless, their expressions in prostate cancer need further investigation. MATERIALS AND METHODS Mucin 1 ...

ةـصلاخلا : يوتحت لا و ةضفخنملا ةقاطلا تاذ تادحولا نم ديدعلا ىلع ةيكلسلالا تارعشتسملا ةكبش ةلصوب ةدوزم سلا ةيكل ثيح ، اهنيب اميف لاصتلال إ نكمي تارعشتسملا كلت ن دختسا ا اهم تا قيبطتلا نم د يدعلا يف . م ت د قو ا هتبقارم دار ملا ة قطنملا ى لع يئاوشع لكشب تارعشتسملا عيزوت ثحبلا اذه يف ا م لكش ب اهميس قت و إ ى ل ةدحاو لآ يوتحت ثيح ،ةقرفتم تانايب دعاوقآ لمعتل تاعومجم ة يناكم تا نايب ى لع تارعش تسمل...

Extracellular matrix (ECM) remodeling is a key component of cell migration and tumor metastasis, and has been associated with cancer progression. Despite the importance of matrix remodeling, systematic and quantitative studies on the process have largely been lacking. Furthermore, it remains unclear if the disrupted tensional homeostasis characteristic of malignancy is due to initially altered ...

Aggregation of attachment-dependent animal cells represents a series of motility, collision, and adhesion events applicable to such diverse fields as tissue engineering, bioseparations, and drug testing. Aggregation of human prostate cancer cells in liquid-overlay culture was modeled using Smoluchowski's collision theory. Using well (LNCaP) and poorly differentiated (DU 145 and PC 3) cell lines...

antiproliferative protein (app) isolated from conditioned media of two androgen-independent prostatic carcinoma cell lines, pc3 and du-145 was shown to inhibit selectively cell proliferation of androgen-dependent prostate cancer cell line lncap in a dose dependent manner. this protein was further purified with hplc using hydrophobic interaction column (phenyl 5pw) and was used to study the modu...