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Description 540 and 673 amino acids, 62 and 74 kDa (PLZFa and b respectively); Krüppel-like zinc finger protein; N-term BTB/POZ domain (protein-protein interaction motif) and 9 zinc finger domains in C-term. Expression Highly specific for hematopoietic cells; during mouse development, PLZF is expressed in embryonic tissus, giving rise to hematopoietic progenitors; in man, PLZF is expressed in C...

background and objectives: some of the human papillomaviruses (hpvs) can infect genital tracts and are sometimes associated with anogenital tract cancers. hpvs induced cervical cancers through the expression of e6 and e7 genes by inactivating the tumor suppressor proteins. in this study, e6 and e7 genes were chosen in order to construct an expression vector which is able to express target prote...

A great advance in physics came when it was realized that it was better to think about motion in empty space rather than starting with what happen in the “real world” with gravity pulling things downwards, friction slowing things down, etc. First, that the laws of physics should be the same at one point as at another, i.e. that they are translation invariant, and also from one day to another, i...

The liver is involved in the synthesis and metabolism of many kinds of hormones, various abnormalities hormone levels are found in advanced liver disease. For example the liver is, extremely sensitive to changes in insulin or glucagon levels. The liver is the primary organ of iron storage is frequently involved, diabetes is common in patients with iron overload and may be seen in cirrhosis. Chr...

inv(16)(p13q22) Gbanding (left) Courtesy Jean-Luc Lai and Alain Vanderhaegen; Rbanding center bottom: Courtesy Christiane Charrin, center top and FISH (top right) -Courtesy Pascale Cornillet-Lefebvre and Stephanie Struski; FISH (bottom right) Courtesy Hossein Mossafa; commercial FISH probes, split in the inv(16). t(16;16)(p13;q22) G-banding Courtesy Diane H. Norback, Eric B. Johnson, and Sara M...