BACKGROUND We performed a meta-analysis of randomized controlled trials (RCTs) to determine if daily bathing with chlorhexidine decreased hospital-acquired BSIs in critically ill patients. METHODS We searched the MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases to identify randomized controlled trials that compared daily bathing with chlorhexidine and a control in...

Editor—We read the article on the national audit conducted by the Royal College of Anaesthetists by Cook and colleagues 1 and congratulate the group on an outstanding piece of work which has enlightened the whole anaesthetic community and no doubt will lead to improved patient safety. We note that the NAP3 audit reinforces that sterile technique in regional anaesthesia is an important aspect of...

To the Editors:Your concerns regarding the recently published study, ‘‘A randomized trial that compared povidone iodine and chlorhexidine as antiseptics for vaginal hysterectomy,’’ are appreciated. First, by way of clarification, the literature search to which you refer did retrieve studies in which vaginal chlorhexidine had been used. In fact, we found 3 studies (including a total of more than...

BACKGROUND Ventilator-associated pneumonia (VAP) is common in critical patients and related with increased morbidity and mortality. We conducted a systematic review and meta-analysis, with intention-to-treat analysis, of randomized controlled clinical trials that assessed the effectiveness of different intraoral chlorhexidine protocols for the prevention of VAP. METHODS Search strategies were...

Introduction Root canal irrigants play an important role in reducing intracanal microorganisms, which in turn helps in achieving a successful outcome for the root canal treatment. Objective To compare the antibacterial efficacy of alexidine and chlorhexidine against Enterococcus faecalis. Methods A total of 50 extracted single-rooted teeth were randomly divided into five groups after being infe...

BACKGROUND & AIMS Catheter-related-blood-stream-infection (CRBSI) might be prevented by optimal catheter connector antisepsis in children with intestinal failure on parenteral nutrition (PN). We changed the disinfectant used from isopropanol 70% to chlorhexidine 2% in 70% isopropanol, which leaves a residue of chlorhexidine on the connector. METHODS We conducted this before/after study in chi...

AIMS Our purpose was to systematically review the literature on the effectiveness of chlorhexidine varnish for preventing dental caries in children and adolescents and to determine its effectiveness compared to fluoride varnish. METHODS MEDLINE, EMBASE and the Cochrane Library were searched through December 2009 to identify relevant randomised trials with blind outcome assessment and a minimu...

AIM The purpose of this study was to compare the antibacterial efficacy of three root canal irrigating solutions: An antibiotic containing irrigant, Chlorhexidine and Chlorhexidine + Cetrimide. METHODOLOGY 46 permanent maxillary central incisors were made into standardized segments and sterilized. 6 teeth were used to confirm sterility. The remaining 40 teeth were infected with Enterococcus f...

Introduction: A great interest regarding 2% chlorhexidine solution is over its efficiency on gram-negative bacteria, but chlorhexidine sensitive microorganisms include gram-positive bacteria, gram-negative bacteria and fungi. The aim of the study was to analyze the antimicrobial and antifungal action of 2% chlorhexidine solution against the microorganisms isolated from infected root canals befo...