The title compound, C(17)H(12)ClNO(2), crystallizes with two mol-ecules in the asymmetric unit. The main conformational difference between these two mol-ecules is the dihedral angle between the phenyl ring and the quinoline ring system [70.5 (1)° and 65.5 (1) Å]. The crystal packing is stabilized by N-H⋯O hydrogen bonds.

The non-H atoms of the title compound, C(10)H(11)ClN(2)O(2), lie nearly on a plane (r.m.s. deviation = 0.150 Å), and the C=N double bond has a Z configuration. In the crystal, adjacent mol-ecules are linked by an N-H⋯O(carbon-yl) hydrogen bond, forming a chain running along [201].

The non-H atoms of the title compound, C(9)H(8)Cl(2)N(2)O, lie nearly on a plane (r.m.s. deviation = 0.110 Å), and the C=N double bond has a Z configuration. In the crystal, adjacent mol-ecules are linked by an N-H⋯O(carbon-yl) hydrogen bond, forming a chain running along [100].

a new 2-[(4-substituted-phenyl-3-chloroazetidin-2-one)-5-(2'-methylamino 4-phenyl-1', 3'-thiazolyl-]-1, 3, 4-thiadiazoles, 5(a-n) were synthesized from 2-substituted-benzylideneamino-5-[2'-methylamino-4'-phenyl-1',3'-thiazolyl]-1,3, 4-thiadiazole, 4(a-n) using 2-amino-4phenyl-1, 3-thiazole as a starting material. the synthesised compounds have been screened in vitro for their antimicrobial acti...

The asymmetric unit of the title compound, C(10)H(11)ClN(2)O, contains two mol-ecules. The non-H atoms of each mol-ecule lie approximately on a plane (r.m.s. deviations = 0.062 and 0.110 Å), and the C=N double bond has a Z-configuration in both independent mol-ecules. In the crystal, adjacent mol-ecules are linked by N-H⋯O(carbon-yl) hydrogen bonds, forming chains running along [100].

Overexpression of mutant p53 in cancer cell inactivates the pathways to execute apoptosis and cycle arrest. This study aimed synthesize new kardiena derivative compound, 3-carbethoxy-4(3’-chloro-4’-hydroxy)phenyl-but-3-en-2-one, reactivate Characterization synthetic compound employing melting point, IR, EI-MS, 1H-NMR, 13C-NMR spectra revealed 3-carbethoxy-4(3’-chloro-4’-hydroxy)phenyl-but-3-en-...

The non-H atoms of the title compound, C(9)H(8)ClN(3)O(3), lie approximately on a plane (r.m.s. deviation = 0.111 Å), and the C=N double bond has a Z configuration. In the crystal, adjacent mol-ecules are linked by an N-H⋯O(carbon-yl) hydrogen bond, forming a chain running along [101].

A facile one-pot method with good yield for the synthesis of 2,4-dichloroquinoline and some related new derivatives by condensation of the appropriate primary aromatic amine with malonic acid in presence of excess phosphorus oxychloride is described.