We have previously reported that the EVn-50 mixture of vitexins (lignan compounds) containing the purified vitexin (neolignan) compound, 6-hydroxy-4(4-hydroxy-3-methoxyphenyl)-3-hydroxymethyl‑7-methoxy-3,4-dihydro-2-naphthaldehyde, termed VB1, exhibits potent anticancer activity through the induction of apoptosis in several types of cancer cells, including MDA-MB‑231 cells. However, the exact m...

2-[3-(2-Formylnaphthoxy)-2-hydroxypropoxy] naphthaldehyde (1) have been prepared by reaction of 2-hydroxynaphthaldehyde with 1,3-dichloro-2-propanol. New N2O3 macro-acyclic ligands (L1, L2) synthesized from the reaction of (1) with aniline or cyclohexylamine. Ni (II), Co (II) and Cu (II) complexes was prepared from reaction of Schiff-bases with metal chloride and nitrate salts. All of these com...

Cu (II) ions, which cause serious diseases such as cancer and liver damage, have an important place, especially in water pollution. To effectively remove these deadly copper ions from aqueous solution, the synthesis of a new functionalized sporopollenin microcapsules (Sp-CPTS-HNMAA) to be used adsorbent was aimed. Schiff base (HNMAA), functionalize surface sporopollenin, obtained result reactio...

Ru(III) Azo Schiff base complexes of the type has been synthesized by the condensation of o-phenylenediamine and 3,5-diaminobenzoic acid with 2-hydroxy naphthaldehyde /vanillin. The complexes were characterized by elemental analyses, molar conductance, magnetic susceptibility, IR, UV spectral data and thermal analyses. The elemental analysis of the complexes confirmed the stoichiometry of the c...

The synthetic molecule sirtinol was shown previously to activate the auxin signal transduction pathway. Here we present a combination of genetic and chemical approaches to elucidate the action mechanisms of sirtinol in Arabidopsis. Analysis of sirtinol derivatives indicated that the "active moiety" of sirtinol is 2-hydroxy-1-naphthaldehyde (HNA), suggesting that sirtinol undergoes a series of t...

Four new bivalent nickel hydrazone complexes have been synthesised from the reactions of [NiCl(2)(PPh(3))(2)] with H(2)L {L = dianion of the hydrazones derived from the condensation of salicylaldehyde or o-hydroxy acetophenone with p-toluic acid hydrazide (H(2)L(1)) (1), (H(2)L(2)) (2) and o-hydroxy acetophenone or o-hydroxy naphthaldehyde with benzhydrazide (H(2)L(3)) (3) and (H(2)L(4)) (4)} a...