I have enjoyed reading the work of each of these authors over the years, so it is a real pleasure to have this opportunity to contribute to the discussion of this collaboration. The geometry of LARS furnishes an elegant bridge between the Lasso and Stagewise regression, methods that I would not have suspected to be so related. Toward my own interests, LARS offers a rather different way to const...

INTRODUCTION To date, no rating scales for detecting apathy in Parkinson's disease (PD) patients have been validated in Spanish. For this reason, the aim of this study was to validate a Spanish version of Lille apathy rating scale (LARS) in a cohort of PD patients from Spain. PARTICIPANTS AND METHODS 130 PD patients and 70 healthy controls were recruited to participate in the study. Apathy wa...

With the growth of the low altitude remote sensing (LARS) industry in recent years, their practical application in precision agriculture seems all the more possible. However, only a few scientists have reported using LARS to monitor crop conditions. Moreover, there have been concerns regarding the feasibility of such systems for producers given the issues related to the post-processing of image...

BACKGROUND Graft choice for anterior cruciate ligament (ACL) reconstruction is of critical importance. Various grafts have been used so far, with autografts long considered the optimal solution for the treatment of ACL-deficient knees. Limited data are available on the long-term survivorship of synthetic grafts. PURPOSE To compare the functional outcome and survivorship of ACL reconstructions...

It is known since the pioneering works of Scheffer and Shnirelman that there are nontrivial distributional solutions to the Euler equations which are compactly supported in space and time. Obviously these solutions do not respect the classical conservation law for the total kinetic energy and they are therefore very irregular. In recent joint works we have proved the existence of continuous and...

OBJECTIVES To investigate how bowel dysfunction after sphincter-preserving rectal cancer treatment, known as low anterior resection syndrome (LARS), is perceived by rectal cancer specialists, in relation to the patient's experience. DESIGN Questionnaire study. SETTING International. PARTICIPANTS 58 rectal cancer specialists (45 colorectal surgeons and 13 radiation oncologists). RESEARCH...

Essential amino acids (EAAs) are potent stimulators of mechanistic target of rapamycin complex 1 (mTORC1) signaling and muscle protein synthesis. However, regulators upstream of mTORC1 that are responsive to EAA availability are not well described, especially in human skeletal muscle. The purpose of this study was to determine changes in leucyl-tRNA synthetase (LARS/LARS) and Ras-related GTP bi...