نتایج جستجو برای: 25 and 30c
تعداد نتایج: 16880985 فیلتر نتایج به سال:
Background To explore the association of genetic polymorphisms in pre-miRNA 30c-1 rs928508 and pre-miRNA 27a rs895819 with non-small-cell lung cancer prognosis. Materials and Methods 480 patients from five hospitals were enrolled in this prospective cohort study. They were followed up for five years. The association between genotypes and overall survival was assessed by Cox proportional hazar...
The plasma level of apolipoprotein B (apoB) is among the strongest risk factors for coronary artery disease. Microsomal triglyceride transfer protein (MTP) plays a key role in the lipidation of nascent apoB and the secretion of apoB-containing lipoproteins enriched with triglycerides and is thus a promising target for the treatment of hyperlipidemia. Yet, the development of MTP inhibitors to lo...
Aberrant miRNA expression has been previously established in breast cancer and has clinical relevance. However, no studies so far have defined miRNAs deregulated in hereditary breast tumors. In this study we investigated the role of miRNAs in hereditary breast tumors comparing with normal breast tissue. Global miRNA expression profiling using Exiqon microarrays was performed on 22 hereditary br...
RATIONALE MicroRNAs (miRNAs), in particular miR-29b and miR-30c, have been implicated as important regulators of cardiac fibrosis. OBJECTIVE To perform a proteomics comparison of miRNA effects on extracellular matrix secretion by cardiac fibroblasts. METHODS AND RESULTS Mouse cardiac fibroblasts were transfected with pre-/anti-miR of miR-29b and miR-30c, and their conditioned medium was ana...
Adult neurogenesis is considered to contribute to a certain degree of plasticity for the brain. However, the effects of adult-born neurons on the brain are still largely unknown. Here, we specifically altered the expression of miR-30c in the subventricular zone (SVZ) and dentate gyrus (DG) by stereotaxic injection with their respective up- and down-regulated lentiviruses. Results showed an incr...
Background: Candida albicans, accounts for more than 75% of all Candidal infections. Apart from its growing prevalence, it is also one the most resistant strains against antifungal medication. Homoeopathy an alternative to allopathic medication and has shown inhibiting fungal growth. Objective: This study was determine effectiveness homoeopathic tinctures medications versus Ketoconazole in grow...
The cultivation of sunflower (Helianthus annuus L.) has significantly increased in recent years, mainly due to the quality of its oil, which is useful for the human consumption and industrial purposes. In order to investigate the effect of different seed storage temperatures on seed quality of two sunflower cultivars (Euorfluor and Rcord), seeds were exposed to three storage temperatures (...
Neuropathic pain and its effective management remains a challenging clinical problem in palliative care of cancer patients. In this study Carcinosinum30c (a homeopathic remedy) is used for relief of severe pain in cancer patients, who were a candidate for nerve block procedure (CEPCA). In this case study to seven cancer patients who were referred to pain clinic for nerve block procedure, after ...
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